1-(4-Chlorophenyl)-2,2-difluoroethan-1-one CAS 655-54-9
| CAS No. | 655-54-9 |
| Molecular Formula | C8H5ClF2O |
| Molecular Weight | 190.57 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
1-(4-Chlorophenyl)-2,2-difluoroethan-1-one (CAS 655-54-9) is a high-purity analytical reference standard with the molecular formula C8H5ClF2O and a molecular weight of 190.57 g/mol.
Owing to a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system, 1-(4-Chlorophenyl)-2,2-difluoroethan-1-one is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 190.57 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO manufactures 1-(4-Chlorophenyl)-2,2-difluoroethan-1-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H5ClF2O |
| Molecular Weight | 190.57 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F/Cl-containing |
Related Chlorophenyl Standards
- 1-(3-Chlorophenyl)-2,2-difluoroethan-1-one (CAS 1271473-74-5)
- 1-(2-Chlorophenyl)-2,2-difluoroethan-1-one (CAS 653-13-4)
- 2-(3-Chlorophenyl)pyrazine (CAS 108030-82-6)
- 4-(4-Chlorophenyl)pyrimidine (CAS 458541-37-2)
- 5-(3-Chlorophenyl)pyrimidine (CAS 74963-05-6)
- 5-(4-Chlorophenyl)pyrimidine (CAS 82525-17-5)
- 4-Chlorophenyl methyl sulfone (CAS 98-57-7)
- 2-(4-chlorophenyl)propanoic acid 4-Chloro-alpha-methylphenylacetic acid 938-95-4 (CAS 938-95-4)
Recommended Standards
- 1-(4-Chloro-2,5-difluorophenyl)ethan-1-one (CAS 655-12-9)
- 2-(4-Chloro-2,3-difluorophenyl)acetaldehyde (CAS 887586-76-7)
- 2,2-Difluoro-2-phenylacetyl chloride (CAS 312-24-3)
- 1-(2-chloro-3,6-difluorophenyl)ethan-1-one (CAS 890934-10-8)
- 2-[(3,5-Difluorophenyl)amino]acetonitrile (CAS 1021238-97-0)
- 2-[(5-Fluoresceinyl)aminocarbonyl]ethyl Methanethiosulfonate (CAS 887355-30-8)
- 3-(((Tetrahydro-2h-pyran-4-yl)methyl)amino)propan-1-ol (CAS 1249495-30-4)
- (E)-N'-(1-(2-Ethoxyphenyl)-2,2,3,3,3-pentafluoropropylidene)-2-(trifluoromethyl)benzenesulfonohydrazide (CAS 2757122-53-3)
- 2-Chloro-4-(3-chlorophenyl)nicotinonitrile (CAS 1225483-73-7)
- 4-Fluoro-2-(methylsulfonyl)aniline (CAS 1197193-21-7)
- Talazoparib Impurity N57 (CAS 1425767-92-5)
- 1,2-Dimethyl-1H-indol-5-amine hydrochloride (CAS 174274-98-7)
- 2-(1-Isopropyl-3-nitro-1H-pyrazol-5-yl)acetonitrile (CAS 1260658-81-8)
- Peptide Impurity 41 (CAS CATO-CPTD788841)
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