2-Bromopyridine-3-carbonyl chloride CAS 654084-12-5

Purity 97%+In StockPharmaceutical Standards
CAS No.654084-12-5
Molecular FormulaC6H3BrClNO
Molecular Weight220.45 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-Bromopyridine-3-carbonyl chloride CAS 654084-12-5 chemical structure

Description

The occurrence of 2-Bromopyridine-3-carbonyl chloride is closely related to an amide group, a hydroxyl group, an ether linkage, chlorine/bromine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

CATO supplies 2-Bromopyridine-3-carbonyl chloride (CAS 654084-12-5), a certified reference material (molecular formula C6H3BrClNO, MW 220.45 g/mol) for analytical method development and quality control.

2-Bromopyridine-3-carbonyl chloride (C6H3BrClNO) contains an amide group, a hydroxyl group, an ether linkage, chlorine/bromine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 2-Bromopyridine-3-carbonyl chloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC6H3BrClNO
Molecular Weight220.45 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)5.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1985
Halogen ContentCl/Br-containing
Nitrogen Atoms1

Related Bromopyridine Standards

Recommended Standards

Why CATO?