Bedaquiline Impurity 5 CAS 654655-68-2
| CAS No. | 654655-68-2 |
| Molecular Formula | C16H11BrClN |
| Molecular Weight | 332.62 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 332.62 g/mol gives Bedaquiline Impurity 5 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Bedaquiline Impurity 5 (CAS 654655-68-2) is a certified pharmaceutical impurity reference standard with the molecular formula C16H11BrClN and a molecular weight of 332.62 g/mol.
Structurally, Bedaquiline Impurity 5 (C16H11BrClN) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine/bromine substitution. The molecule exhibits a degree of unsaturation (DBE) of 11.0, corresponding to approximately 11 ring(s) or double-bond equivalent(s). With a molecular weight of 332.62 g/mol, it falls into the moderately-high-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Bedaquiline Impurity 5 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C16H11BrClN |
| Molecular Weight | 332.62 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | Cl/Br-containing |
| Nitrogen Atoms | 1 |
Related Bedaquiline Standards
- Bedaquiline Impurity 63 (CAS 2813341-31-8)
- Bedaquiline Impurity 16 (CAS 918648-51-8)
- Bedaquiline Impurity 17 (CAS 918518-83-9)
- Bedaquiline Impurity 4 (CAS 654655-69-3)
- Bedaquiline Impurity N1 (CAS 39648-67-4)
- Bedaquiline Impurity 4 (CAS 924633-09-0)
- Bedaquiline Impurity 1 (CAS 349537-52-6)
- Bedaquiline Impurity 6 (CAS 316146-27-7)
Recommended Standards
- 72802-79-0 Carbon-13C tetrabromide DTXSID00482569 (CAS 72802-79-0)
- 2,5-Bis((trimethylsilyl)ethynyl)thieno[3,2-b]thiophene (CAS 139896-65-4)
- 3-Benzyl-7-bromo-2-chloroquinoline (CAS 918518-81-7)
- 1-(1-(2-Chlorophenyl)ethyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole (CAS 1604036-78-3)
- Doxapram Impurity 17 (CAS CATO-C4X-197317)
- Epinephrine Impurity 68 (CAS CATO-C4X-184968)
- Bosentan Impurity 02 (CAS 301646-61-7)
- 2-[(furan-2-ylmethyl)amino]benzonitrile (CAS 204078-98-8)
- Sodium 2-((2-(stearoyloxy)propanoyl)oxy)propanoate (CAS 25383-99-7)
- 3,6,9,12,15-Pentaoxanonadecan-1-ol (CAS 1786-94-3)
- n-Butyl-4-fluoroaniline (CAS 101906-10-9)
- Methyl 3-amino-2,2-dibenzylpropanoate hydrochloride (CAS 1255098-73-7)
- 2-[(7-Nitro-2,1,3-benzoxadiazol-4-yl)amino]ethanethiol (CAS 50540-16-4)
- Semaglutide impurity 108 (CAS CATO-C4X-2226108)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com