3-(4-Chlorophenyl)-2,4-difluoropropiophenone CAS 654673-29-7

Purity 97%+In StockPharmaceutical Standards
CAS No.654673-29-7
Molecular FormulaC15H11ClF2O
Molecular Weight280.70 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

3-(4-Chlorophenyl)-2,4-difluoropropiophenone CAS 654673-29-7 chemical structure

Description

The occurrence of 3-(4-Chlorophenyl)-2,4-difluoropropiophenone is closely related to a hydroxyl group, an ether linkage, fluorine/chlorine substitution, a polycyclic aromatic system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

3-(4-Chlorophenyl)-2,4-difluoropropiophenone (CAS 654673-29-7), molecular formula C15H11ClF2O and molecular weight 280.70 g/mol, is a CATO reference standard with documented purity and traceability.

Owing to a hydroxyl group, an ether linkage, fluorine/chlorine substitution, a polycyclic aromatic system, 3-(4-Chlorophenyl)-2,4-difluoropropiophenone is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 280.70 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 3-(4-Chlorophenyl)-2,4-difluoropropiophenone meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC15H11ClF2O
Molecular Weight280.70 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)9.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1985
Halogen ContentF/Cl-containing

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Why CATO?