3-(4-Chlorophenyl)-3,4-difluoropropiophenone CAS 898788-47-1
| CAS No. | 898788-47-1 |
| Molecular Formula | C15H11ClF2O |
| Molecular Weight | 280.70 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 3-(4-Chlorophenyl)-3,4-difluoropropiophenone is closely related to a hydroxyl group, an ether linkage, fluorine/chlorine substitution, a polycyclic aromatic system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 3-(4-Chlorophenyl)-3,4-difluoropropiophenone (CAS 898788-47-1), a certified reference material (molecular formula C15H11ClF2O, MW 280.70 g/mol) for analytical method development and quality control.
The molecular framework of 3-(4-Chlorophenyl)-3,4-difluoropropiophenone (C15H11ClF2O) is characterized by a hydroxyl group, an ether linkage, fluorine/chlorine substitution, a polycyclic aromatic system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C15H11ClF2O |
| Molecular Weight | 280.70 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F/Cl-containing |
Related Chlorophenyl Standards
- 3-(3-Chlorophenyl)-1-(3,5-difluorophenyl)propan-1-one (CAS 898787-46-7)
- 3-(3-Chlorophenyl)-2,4-difluoropropiophenone (CAS 898787-42-3)
- 3-(3-Chlorophenyl)-3,4-difluoropropiophenone (CAS 898787-44-5)
- 3-(4-Chlorophenyl)-1-(3,5-difluorophenyl)propan-1-one (CAS 898788-49-3)
- 3-(4-Chlorophenyl)-2,4-difluoropropiophenone (CAS 654673-29-7)
- Ethyl 3-[5-(4-chlorophenyl)-1,3,4-oxadiazol-2-yl]propanoate (CAS 1240527-55-2)
- Methyl 4-(2-chlorophenyl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate (CAS 159587-52-7)
- (1-(4-Chlorophenyl)-1H-1,2,3-triazol-4-yl)methyl ethylcarbamate (CAS 338419-15-1)
Recommended Standards
- 3-[(2-Chloro-4-fluorobenzyl)sulfonyl]-propanoic acid (CAS 702670-31-3)
- 3-Chloro-4-fluoro-3-(4-fluorophenyl)-propiophenone (CAS 898768-49-5)
- 3-Chloro-5-fluoro-3-(3-fluorophenyl)propiophenone (CAS 898767-53-8)
- 4-Chloro-2-fluoro-3-(4-fluorophenyl)propiophenone (CAS 898768-66-6)
- N1-(2-chloro-6-fluorobenzyl)-N3,N3-dimethylpropane-1,3-diamine (CAS 893593-06-1)
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