Terbinafine EP Impurity A HCl CAS 65473-13-4
| CAS No. | 65473-13-4 |
| Molecular Formula | C12H13N |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 207.70 g/mol gives Terbinafine EP Impurity A HCl distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies Terbinafine EP Impurity A HCl (CAS 65473-13-4), a pharmacopoeial impurity reference standard (molecular formula C12H13NHCl, MW 207.70 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Terbinafine EP Impurity A HCl (C12H13NHCl) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 6.0, corresponding to approximately 6 ring(s) or double-bond equivalent(s). With a molecular weight of 207.70 g/mol, it falls into the medium-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Terbinafine EP Impurity A HCl under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H13N HCl |
| Molecular Weight | 207.70 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1975 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Terbinafine Standards
- Terbinafine Hydroxy Benzoate (CAS 1076198-30-5)
- Terbinafine Carboxylic Acid Methyl Ester (Oxalate) (CAS 1076199-76-2)
- Terbinafine Impurity 4 (Mixture of Z and E Isomers) (CAS 114311-70-5)
- Terbinafine Impurity 5-d7 (CAS 1185238-58-7)
- Terbinafine-d7 Hydrochloride (CAS 1185240-27-0)
- Terbinafine Impurity 4 (CAS 125660-64-2)
- Terbinafine Impurity 10 (CAS 126764-17-8)
- Terbinafine-d3 HCl (N-methyl-d3) (CAS 1310012-15-7)
Recommended Standards
- Carteolol Impurity 40 (CAS CATO-C4X-228740)
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- 3-(1H-Indol-3-yl)-2-[(thiophene-2-carbonyl)-amino]-propionic acid (CAS 1396966-01-0)
- Bedaquiline Impurity 65 (Mixture of Enantiomers) (CAS CATO-C4X-116765)
- Methyl 4-amino-2-(pyridin-3-ylamino)thiazole-5-carboxylate (CAS 1858251-02-1)
- (4-Methyl-3-nitropyridin-2-yl)methanol (CAS 21203-57-6)
- (Ser(PO3H2)202,Thr(PO3H2)205)-Tau Peptide (194-213) trifluoroacetate salt (CAS 2022956-55-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com