Terbinafine Impurity 5-d7 CAS 1185238-58-7
| CAS No. | 1185238-58-7 |
| Molecular Formula | - |
| Molecular Weight | 314.43 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Terbinafine Impurity 5-d7 (CAS 1185238-58-7) is a high-purity analytical reference standard with the molecular formula C20H14D7NO2 and a molecular weight of 314.43 g/mol.
The molecular framework of Terbinafine Impurity 5-d7 (C20H14D7NO2) is characterized by deuterium isotope labeling, a steroid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C20H14D7NO2 |
| Molecular Weight | 314.43 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 14.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Nitrogen Atoms | 1 |
Related Terbinafine Standards
- Terbinafine Impurity 1 (CAS 134274-69-4)
- Terbinafine Impurity 6 (CAS 99473-14-0)
- Terbinafine Impurity 48 (CAS CATO-C4X-133848)
- Terbinafine Impurity 49 (CAS CATO-C4X-133849)
- Terbinafine Impurity N2 (CAS 99473-15-1)
- Terbinafine impurity 34 (CAS CATO-C4X-133834)
- Terbinafine Impurity 31 (CAS CATO-C4X-133831)
- Terbinafine EP Impurity D (CAS 151222-50-3)
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