(5E)-5-(2,6-Dichlorobenzylidene)-2-mercapto-1,3-thiazol-4(5H)-one CAS 65562-49-4

Purity 97%+In StockPharmaceutical Standards
CAS No.65562-49-4
Molecular FormulaC10H5Cl2NOS2
Molecular Weight290.19 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

(5E)-5-(2,6-Dichlorobenzylidene)-2-mercapto-1,3-thiazol-4(5H)-one CAS 65562-49-4 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 290.19 g/mol gives (5E)-5-(2,6-Dichlorobenzylidene)-2-mercapto-1,3-thiazol-4(5H)-one distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

(5E)-5-(2,6-Dichlorobenzylidene)-2-mercapto-1,3-thiazol-4(5H)-one (CAS 65562-49-4) is a high-purity analytical reference standard with the molecular formula C10H5Cl2NOS2 and a molecular weight of 290.19 g/mol.

The molecular framework of (5E)-5-(2,6-Dichlorobenzylidene)-2-mercapto-1,3-thiazol-4(5H)-one (C10H5Cl2NOS2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC10H5Cl2NOS2
Molecular Weight290.19 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)8.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1975
Halogen ContentCl-containing
Nitrogen Atoms1
Sulfur Atoms2

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