5-Chloro-2-(trifluoromethyl)-1H-benzo[d]imidazole CAS 656-49-5
| CAS No. | 656-49-5 |
| Molecular Formula | C8H4ClF3N2 |
| Molecular Weight | 220.58 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
5-Chloro-2-(trifluoromethyl)-1H-benzo[d]imidazole (CAS 656-49-5), molecular formula C8H4ClF3N2 and molecular weight 220.58 g/mol, is a CATO reference standard with documented purity and traceability.
5-Chloro-2-(trifluoromethyl)-1H-benzo[d]imidazole (C8H4ClF3N2) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO manufactures 5-Chloro-2-(trifluoromethyl)-1H-benzo[d]imidazole under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H4ClF3N2 |
| Molecular Weight | 220.58 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloro Standards
- 3-Chloro-6-(trifluoromethyl)-1H-indazole (CAS 1000341-24-1)
- 4-chloro-2-(trifluoromethyl)-1H-pyrrolo[2,3-b]pyridine (CAS 1014613-16-1)
- 3-Chloro-6-(trifluoromethyl)imidazo[1,2-a]pyridine (CAS 1019027-76-9)
- 5-Chloro-2-(trifluoromethyl)benzofuran (CAS 1067238-68-9)
- 2-Chloro-7-(trifluoromethyl)-1H-benzo[d]imidazole (CAS 1075753-27-3)
- 2-Chloro-6-(trifluoromethyl)imidazo[1,2-a]pyridine (CAS 112601-16-8)
- 3-Chloro-5-(trifluoromethyl)-1H-pyrrolo[3,2-b]pyridine (CAS 1190312-01-6)
- 3-Chloro-6-(trifluoromethyl)-1H-pyrrolo[3,2-b]pyridine (CAS 1190319-49-3)
Recommended Standards
- 4-Chloro-2-(difluoromethyl)-5-fluoro-1H-pyrrolo[2,3-b]pyridine (CAS 2092048-48-9)
- 5-Chloro-3-(trifluoromethyl)-1H-indazole (CAS 57631-13-7)
- 4-Amino-5-chloro-2-(trifluoromethyl)benzonitrile (CAS 888073-09-4)
- 5-Chloro-7-(trifluoromethyl)imidazo[1,5-a]pyridine (CAS 2064217-73-6)
- Hexadecyltrimethylammonium (perchlorate) (CAS 6941-37-3)
- 2-Bromo-6-(cyclohexyloxy)pyridine (CAS 959237-74-2)
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