2,2-Difluoro-1,3-benzodioxole-5-carboxylic Acid CAS 656-46-2
| CAS No. | 656-46-2 |
| Molecular Formula | C8H4F2O4 |
| Molecular Weight | 202.11 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2,2-Difluoro-1,3-benzodioxole-5-carboxylic Acid is closely related to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
2,2-Difluoro-1,3-benzodioxole-5-carboxylic Acid (CAS 656-46-2) is a high-purity analytical reference standard with the molecular formula C8H4F2O4 and a molecular weight of 202.11 g/mol.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system, 2,2-Difluoro-1,3-benzodioxole-5-carboxylic Acid is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 202.11 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 2,2-Difluoro-1,3-benzodioxole-5-carboxylic Acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H4F2O4 |
| Molecular Weight | 202.11 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
Related Difluoro Standards
- 2,4-Difluoro-5-nitrobenzamide (CAS 1097799-57-9)
- 2,6-Difluoro-3-nitrobenzamide (CAS 124169-54-6)
- 3,5-Difluoro-4-nitrobenzamide (CAS 1260882-93-6)
- 2,5-Difluoro-3-nitrobenzamide (CAS 1701869-33-1)
- 2,4-Difluoro-6-nitrobenzamide (CAS 1803809-01-9)
- 2,6-Difluoro-4-nitrobenzamide (CAS 1803826-50-7)
- 3,5-Difluoro-2-nitrobenzamide (CAS 1806335-19-2)
- 2,3-Difluoro-5-nitrobenzamide (CAS 1806388-74-8)
Recommended Standards
- Nitrofurazone-13C,15N3 (CAS 1958113-24-0)
- 2,5-Difluoroterephthalic acid (CAS 655-14-1)
- 4,5-Difluorophthalic acid (CAS 18959-31-4)
- 3,6-Difluorophthalic Acid (CAS 651-97-8)
- Epoxymicheliolide (CAS 1343403-10-0)
- n-[4-chloro-3-(3-chloropropyl)-5-formyl-2,3-dihydro-1,3-thiazol-2-ylidene]benzenesulfonamide (CAS 723320-46-5)
- 2-Ethyl-N-(1-(pyridin-3-yl)ethyl)butan-1-amine (CAS 1038226-23-1)
- 3＇,5＇-Dimethylacetophenone (CAS 5379-16-8)
- 1-Oxo-14,17,20,23-tetraoxa-2-thiapentacosan-25-oic acid (CAS 1262769-96-9)
- Danazol Impurity 13 (CAS 121565-23-9)
- Cinnamonitrile (CAS 1885-38-7)
- H-Arg-Gln-OH (CAS 2483-17-2)
- (S)-3-(3-Acetyl-4-hydroxyphenyl)-2-aminopropanoic acid (CAS 32483-30-0)
- Semaglutide impurity 36 (CAS CATO-C4X-222636)
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