8-Dimethylamino-1,4-dioxaspiro[4.5]decan-8-carbonitrile CAS 65619-92-3

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 8-Dimethylamino-1,4-dioxaspiro[4.5]decan-8-carbonitrile.

8-Dimethylamino-1,4-dioxaspiro[4.5]decan-8-carbonitrile (CAS 65619-92-3), molecular formula C11H18N2O2 and molecular weight 210.27 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 8-Dimethylamino-1,4-dioxaspiro[4.5]decan-8-carbonitrile (C11H18N2O2) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures 8-Dimethylamino-1,4-dioxaspiro[4.5]decan-8-carbonitrile under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

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