4-(4-Fluorophenyl)-5-hydroxyisoquinolin-1(2H)-one CAS 656234-22-9
| CAS No. | 656234-22-9 |
| Molecular Formula | C15H10FNO2 |
| Molecular Weight | 255.24 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
4-(4-Fluorophenyl)-5-hydroxyisoquinolin-1(2H)-one (CAS 656234-22-9), molecular formula C15H10FNO2 and molecular weight 255.24 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, 4-(4-Fluorophenyl)-5-hydroxyisoquinolin-1(2H)-one is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 255.24 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), 4-(4-Fluorophenyl)-5-hydroxyisoquinolin-1(2H)-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C15H10FNO2 |
| Molecular Weight | 255.24 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Fluorophenyl Standards
- 1-(3-(3-Fluorophenyl)benzo[c]isoxazol-5-yl)ethan-1-one (CAS 383147-36-2)
- 1-(4-FLUOROPHENYL)-1H-INDOLE-5-CARBOXYLICACID (CAS 243467-60-9)
- 1-[3-(4-Fluorophenyl)-2,1-benzoxazol-5-yl]ethan-1-one (CAS 306978-23-4)
- 2-(2-Fluorophenyl)-6-methyl-4H-benzo[d][1,3]oxazin-4-one (CAS 301193-57-7)
- 2-(4-Fluorophenyl)-1H-indole-3-carboxylic acid (CAS 773870-18-1)
- 2-(4-Fluorophenyl)-1H-indole-4-carboxylic acid (CAS 917614-77-8)
- 2-(4-Fluorophenyl)indolizine-1-carboxylic acid (CAS 477889-04-6)
- 2-[(3-Fluorophenyl)methyl]isoindole-1,3-dione (CAS 70216-78-3)
Recommended Standards
- 4-(4-(Trifluoromethyl)phenyl)tetrahydro-2H-pyran-4-carbonitrile (CAS 473706-06-8)
- 4-(Piperazin-1-yl)-2-(trifluoromethyl)benzonitrile (CAS 262295-57-8)
- 4-(3-Fluorophenyl)-5-hydroxyisoquinolin-1(2H)-one (CAS 656234-21-8)
- 6-Methyl-2-(pyrrolidin-1-yl)-4-(trifluoromethyl)nicotinonitrile (CAS 478049-77-3)
- N,N-Dimethyl-6-pyrrolidin-2-ylpyridine-2-carboxamide dihydrochloride (CAS 2109104-07-4)
- pyrimidine-4-carboximidamide dihydrochloride (CAS 1989659-39-3)
- 2-{3-[(4-tert-butylphenyl)methyl]-4-oxo-3,4-dihydrophthalazin-1-yl}acetic acid (CAS 866151-30-6)
- 1-(Piperidin-3-yl)-4,5,6,7-tetrahydro-1H-benzo[d][1,2,3]triazole (CAS 1774904-15-2)
- (R)-Benzyloxycarbonylamino-cyclopropyl-acetic acid (CAS 1260593-73-4)
- (2,2-Dimethoxyethyl)(m-tolyl)sulfane (CAS 57860-49-8)
- Tofacitinib Impurity 121 (CAS 1228879-37-5)
- 8-Bromo-2,3-dihydrobenzo[b]oxepin-4(5H)-one (CAS 1781966-83-3)
- 4-Azaspiro[2.4]hepta-1,4,6-triene (CAS 926283-34-3)
- Des-His(1)-Semaglutide (CAS CATO-C4X-2226216)
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