Nintedanib Esylate CAS 656247-18-6
| CAS No. | 656247-18-6 |
| Molecular Formula | C31H33N5O4 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Nintedanib Esylate is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies Nintedanib Esylate (CAS 656247-18-6), a certified reference material (molecular formula C31H33N5O4C2H6O3S, MW 649.76 g/mol) for analytical method development and quality control.
Structurally, Nintedanib Esylate (C31H33N5O4C2H6O3S) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 17.0, corresponding to approximately 17 ring(s) or double-bond equivalent(s). With a molecular weight of 649.76 g/mol, it falls into the high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), Nintedanib Esylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C31H33N5O4 C2H6O3S |
| Molecular Weight | 649.76 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 17.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Nitrogen Atoms | 5 |
| Sulfur Atoms | 1 |
Related Nintedanib Standards
- Nintedanib Impurity 158 (CAS 1023942-14-4)
- Nintedanib Impurity 9 (CAS 1038972-16-5)
- Nintedanib Impurity 156 (CAS 1040320-04-4)
- Nintedanib Impurity 19 (CAS 1125-88-8)
- Nintedanib Impurity 6 (CAS 1139453-98-7)
- Nintedanib Impurity N24 (CAS 1139455-52-9)
- Nintedanib Impurity N10 (CAS 1139457-10-5)
- Nintedanib Impurity N8 (CAS 1139458-48-2)
Recommended Standards
- dimethyl trans-4-oxocyclopentane-1,2-dicarboxylate (CAS 28269-03-6)
- Bromo-PEG2-C2-Boc (CAS 1381861-91-1)
- 1-Methyl-N-(1-methylpyrrolidin-3-yl)piperidin-4-amine (CAS 1247193-34-5)
- 4-Bromo-2-chlorobenzoyl chloride (CAS 21900-55-0)
- (E)-2-Cyano-3-(dimethylamino)acrylamide (CAS 120650-89-7)
- Trimethylolpropane Tris(thioglycolate) (CAS 10193-96-1)
- Imidazo[1,5-a][1,3,5]triazine-2,4-diamine (CAS 557791-38-5)
- Ethyl 2-[(3,5-dimethylphenyl)carbamoyl]acetate (CAS 104330-56-5)
- Ursodeoxycholic Impurity 14 (CAS 345909-26-4)
- Semaglutide impurity 269 (CAS CATO-C4X-2226269)
Why CATO?
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