2',6'-Difluoro-[1,1'-biphenyl]-3-carboxylic acid CAS 656305-06-5

Purity 97%+In StockPharmaceutical Standards
CAS No.656305-06-5
Molecular FormulaC13H8F2O2
Molecular Weight234.20 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2',6'-Difluoro-[1,1'-biphenyl]-3-carboxylic acid CAS 656305-06-5 chemical structure

Description

The occurrence of 2',6'-Difluoro-[1,1'-biphenyl]-3-carboxylic acid is closely related to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

CATO supplies 2',6'-Difluoro-[1,1'-biphenyl]-3-carboxylic acid (CAS 656305-06-5), a certified reference material (molecular formula C13H8F2O2, MW 234.20 g/mol) for analytical method development and quality control.

Structurally, 2',6'-Difluoro-[1,1'-biphenyl]-3-carboxylic acid (C13H8F2O2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 9.0, corresponding to approximately 9 ring(s) or double-bond equivalent(s). With a molecular weight of 234.20 g/mol, it falls into the medium-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures 2',6'-Difluoro-[1,1'-biphenyl]-3-carboxylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC13H8F2O2
Molecular Weight234.20 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)9.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1985
Halogen ContentF-containing

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