6-(2-Fluorobenzyl)-5,7-dimethylpyrazolo[1,5-a]pyrimidine-3-carboxylic acid CAS 656818-36-9
| CAS No. | 656818-36-9 |
| Molecular Formula | C16H14FN3O2 |
| Molecular Weight | 299.30 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 299.30 g/mol gives 6-(2-Fluorobenzyl)-5,7-dimethylpyrazolo[1,5-a]pyrimidine-3-carboxylic acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
6-(2-Fluorobenzyl)-5,7-dimethylpyrazolo[1,5-a]pyrimidine-3-carboxylic acid (CAS 656818-36-9), molecular formula C16H14FN3O2 and molecular weight 299.30 g/mol, is a CATO reference standard with documented purity and traceability.
Based on its molecular formula C16H14FN3O2, 6-(2-Fluorobenzyl)-5,7-dimethylpyrazolo[1,5-a]pyrimidine-3-carboxylic acid contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 299.30 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C16H14FN3O2 |
| Molecular Weight | 299.30 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Fluorobenzyl Standards
- 1172715-09-1 1-(4-Fluorobenzyl)-2-oxo-1,2,3,4-tetrahydroquinoline-6-carboxylic acid MFCD14281841 (CAS 1172715-09-1)
- 1-(4-Fluorobenzyl)-3-(2-oxoindolin-5-yl)urea (CAS 1173054-34-6)
- 3-(4-Fluorobenzyl)-1-(furan-2-ylmethyl)-4-hydroxypyridin-2(1H)-one (CAS 477856-07-8)
- N-(2-Fluorobenzyl)-3-(pyrazin-2-yl)-1,2,4-oxadiazole-5-carboxamide (CAS 1234851-41-2)
- 3-(2-Fluorobenzyl)-7-nitroquinazolin-4(3H)-one (CAS 728886-80-4)
- 1-Benzyl-4-(2-fluorobenzyl)piperidin-4-ol (CAS 71916-70-6)
- 2-(4-Fluorobenzyl)-5-nitroisoindoline-1,3-dione (CAS 337474-19-8)
- N-(4-Fluorobenzyl)-3-phenylpyrrolidine-1-carboxamide (CAS 1211023-70-9)
Recommended Standards
- 4-[7-(4-Fluorophenyl)-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl]morpholine (CAS 320416-19-1)
- 7-Fluoro-3-((4-methoxybenzyl)oxy)-1,5-naphthyridin-2-amine (CAS 2435612-32-9)
- 4-[[(6-Nitro-2-benzothiazolyl)imino]methyl]phenol (CAS 905440-97-3)
- Riociguat Impurity N49 (CAS 256376-59-7)
- 4-(5-Piperidin-2-yl-1,2,4-oxadiazol-3-yl)pyridine dihydrochloride (CAS 1036531-34-6)
- 1-(1-Ethyl-1H-imidazol-5-yl)ethanone (CAS 602306-51-4)
- N-(4-((Methylthio)methyl)thiazol-2-yl)cyclopentanecarboxamide (CAS 955820-54-9)
- AZD-PEG2-PFP (CAS 1807537-41-2)
- Bis [2- (2,4-difluorophenyl) -5-trifluoromethylpyridine] [1,10-phenanthroline] iridium hexafluorophosphate (CAS 1639408-64-2)
- 2-(2-Bromoethyl)piperidine (CAS 731742-05-5)
- 1-(4-Chlorophenyl)-2-methylpropan-1-amine hydrochloride (CAS 72954-91-7)
- tert-Butyl (R)-2-methylpiperazine-1-carboxylate hydrochloride (CAS 1000853-53-1)
- 2-(4-(Difluoromethyl)-6-fluoro-2-methoxypyridin-3-yl)acetonitrile (CAS 1805050-09-2)
- Neuropeptide S (rat) (CAS 412938-75-1)
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