(1,1-Difluoroethyl)benzene CAS 657-35-2
| CAS No. | 657-35-2 |
| Molecular Formula | C8H8F2 |
| Molecular Weight | 142.15 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of (1,1-Difluoroethyl)benzene is closely related to fluorine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies (1,1-Difluoroethyl)benzene (CAS 657-35-2), a certified reference material (molecular formula C8H8F2, MW 142.15 g/mol) for analytical method development and quality control.
(1,1-Difluoroethyl)benzene (C8H8F2) contains fluorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H8F2 |
| Molecular Weight | 142.15 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
Related Difluoroethyl Standards
- (2,2-Difluoroethyl)benzene (CAS 10541-59-0)
- 2-[(2,2-difluoroethyl)sulfanyl]ethan-1-amine (CAS 1183099-68-4)
- 2-(1,1-Difluoroethyl)pyridine (CAS 114468-02-9)
- 3-(1,1-Difluoroethyl)pyridine (CAS 114468-03-0)
- 4-(1,1-Difluoroethyl)pyridine (CAS 114490-29-8)
- (2,2-Difluoroethyl)thiourea (CAS 1274792-12-9)
- 2,2-Difluoroethyl methyl carbonate (CAS 916678-13-2)
- 2,2-Difluoroethyl chloroformate (CAS 111022-16-3)
Recommended Standards
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- 9-(Methoxymethyl)acridine (CAS 62509-63-1)
- 3-Fluoro-5-(4-fluoropyrrolidin-2-yl)pyridine (CAS 2360029-04-3)
- JNJ 10191584 Maleate (CAS 869497-75-6)
- 7-(Tert-butoxycarbonyl)-7-azabicyclo[2.2.1]Hept-2-ene-1-carboxylic acid (CAS 1258511-46-4)
- 2-(3-Ethyl-1,2,4-oxadiazol-5-yl)piperidine hydrochloride (CAS 1385696-71-8)
- 3-Bromo-5-iodobenzotrifluoride (CAS 481075-59-6)
- (4-Hydroxy-1-piperidinyl)(4-piperidinyl)methanonehydrochloride (CAS 1220039-09-7)
- Semaglutide impurity 197 (CAS CATO-C4X-2226197)
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