2-(3,4-Dimethoxyphenyl)piperazine CAS 65709-39-9
| CAS No. | 65709-39-9 |
| Molecular Formula | C12H18N2O2 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
2-(3,4-Dimethoxyphenyl)piperazine (CAS 65709-39-9), molecular formula C12H18N2O2HCl and molecular weight 258.75 g/mol, is a CATO reference standard with documented purity and traceability.
2-(3,4-Dimethoxyphenyl)piperazine (C12H18N2O2HCl) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
CATO manufactures 2-(3,4-Dimethoxyphenyl)piperazine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H18N2O2 2*HCl |
| Molecular Weight | 258.75 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1975 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Dimethoxyphenyl Standards
- [(2,3-dimethoxyphenyl)methyl](ethyl)amine (CAS 100054-84-0)
- 5-(3,5-Dimethoxyphenyl)-3-oxopentanenitrile (CAS 1000895-54-4)
- 6-(3,5-Dimethoxyphenyl)-3-(4-fluorophenyl)-1H-pyrazolo[3,4-b]pyridine (CAS 1001083-74-4)
- 3-(2,5-Dimethoxyphenyl)propanoyl chloride (CAS 100126-94-1)
- 2-(3,5-Dimethoxyphenyl)morpholine (CAS 1001940-37-9)
- (2E)-1-(2,4-Dimethoxyphenyl)-3-[4-(propan-2-yl)phenyl]prop-2-en-1-one (CAS 1002460-32-3)
- (2E)-1-(2,4-Dimethoxyphenyl)-3-(5-methylthiophen-2-yl)prop-2-en-1-one (CAS 1002460-75-4)
- 1-(3,4-Dimethoxyphenyl)butan-1-amine hydrochloride (CAS 100252-51-5)
Recommended Standards
- 2-(4-Bromo-2-fluoro-5-(trifluoromethyl)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 2096337-75-4)
- 4-(Difluoromethoxy)-3-fluorophenylboronic Acid (CAS 958451-69-9)
- (3AR,6aS)-2-(pyridin-2-ylmethyl)octahydropyrrolo[3,4-c]pyrrole (CAS 1690153-64-0)
- 1-(3,4,5-Trifluorophenyl)prop-2-en-1-ol (CAS 1494443-39-8)
- Lysine Impurity 16 (CAS 4272-71-3)
- 4-{[(3,4-Dimethylphenyl)(methylsulfonyl)amino]methyl}benzoic acid (CAS 359020-78-3)
- 5-Chloro-6-methylpicolinic acid (CAS 137778-19-9)
- 2-(Quinolin-5-yl)acetic acid (CAS 152150-03-3)
- 12,13,13,13-Tetradeuterio-12-(trideuteriomethyl)tridecan-1-ol (CAS 1794885-54-3)
- Semaglutide impurity 96 (CAS CATO-C4X-222696)
Why CATO?
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