4-(Difluoromethoxy)-3-fluorophenylboronic Acid CAS 958451-69-9
| CAS No. | 958451-69-9 |
| Molecular Formula | C7H6BF3O3 |
| Molecular Weight | 205.93 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 4-(Difluoromethoxy)-3-fluorophenylboronic Acid is closely related to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
4-(Difluoromethoxy)-3-fluorophenylboronic Acid (CAS 958451-69-9), molecular formula C7H6BF3O3 and molecular weight 205.93 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 4-(Difluoromethoxy)-3-fluorophenylboronic Acid (C7H6BF3O3) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 3.5, corresponding to approximately 3 ring(s) or double-bond equivalent(s). With a molecular weight of 205.93 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 4-(Difluoromethoxy)-3-fluorophenylboronic Acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H6BF3O3 |
| Molecular Weight | 205.93 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.5 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
Related Difluoromethoxy Standards
- (4-(Difluoromethoxy)-2-fluorophenyl)boronic acid (CAS 1004775-34-1)
- (2-(Difluoromethoxy)-5-fluorophenyl)boronic acid (CAS 958451-71-3)
- (3-(Difluoromethoxy)-5-fluorophenyl)boronic acid (CAS 2055539-69-8)
- 2-(Difluoromethoxy)-3-fluorophenylboronic acid (CAS 958451-76-8)
- 2-(Difluoromethoxy)-4-fluorophenylboronic acid (CAS 958451-73-5)
- 3-(Difluoromethoxy)-4-fluorophenylboronic acid (CAS 958451-70-2)
- 2-(Difluoromethoxy)-5-fluorobenzoic acid (CAS 1017779-44-0)
- 4-(Difluoromethoxy)-2-fluorobenzoic acid (CAS 1017779-52-0)
Recommended Standards
- 3-Hydroxy-5-(trifluoromethyl)phenylboronic Acid (CAS 957062-66-7)
- 2-Bromo-2,3,3,3-tetrafluoropropanenitrile (CAS 234443-23-3)
- 3-Hydroxy-4-(trifluoromethyl)phenylboronic acid (CAS 2377610-31-4)
- 3-Bromo-1,1,1-trifluoropropan-2-one oxime (CAS 117341-57-8)
- 4,7-Dibromo-1H-imidazo[4,5-c]pyridin-2(3H)-one (CAS 161836-10-8)
- 2-(2,6,6-Trimethyl-4-oxo-4,5,6,7-tetrahydrobenzofuran-3-yl)acetic acid (CAS 97024-74-3)
- Sodium fumarate-2,3-¹³C2 (CAS 312623-83-9)
- Methyl 2-amino-3-(4,5-dimethyl-1h-imidazol-1-yl)propanoate (CAS 1249260-02-3)
- ELR510444, 98%, a novel microtubule disruptor; inhibits MDA-MB-231 cell proliferation (CAS 1233948-35-0)
- 3,4,4-trimethylpyrrolidin-3-ol (CAS 2742913-62-6)
- 2-Ethoxy-5-{[(thiophen-2-yl)methyl]sulfamoyl}benzoic acid (CAS 866156-10-7)
- 2,4-Dichloro-5-ethoxypyrimidine (CAS 280582-25-4)
- 6,9-Difluoro-1-methyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole (CAS 2408686-91-7)
- D-[Thr]5-Semaglutide (CAS CATO-C4X-2226245)
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