((5-Chloro-2-fluorophenyl)ethynyl)trimethylsilane CAS 657425-05-3
| CAS No. | 657425-05-3 |
| Molecular Formula | C11H12ClFSi |
| Molecular Weight | 226.75 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies ((5-Chloro-2-fluorophenyl)ethynyl)trimethylsilane (CAS 657425-05-3), a certified reference material (molecular formula C11H12ClFSi, MW 226.75 g/mol) for analytical method development and quality control.
The molecular framework of ((5-Chloro-2-fluorophenyl)ethynyl)trimethylsilane (C11H12ClFSi) is characterized by fluorine/chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), ((5-Chloro-2-fluorophenyl)ethynyl)trimethylsilane meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H12ClFSi |
| Molecular Weight | 226.75 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F/Cl-containing |
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
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