5-Methyl-8-nitroquinoline CAS 65745-69-9
| CAS No. | 65745-69-9 |
| Molecular Formula | C10H8N2O2 |
| Molecular Weight | 188.18 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 5-Methyl-8-nitroquinoline meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
5-Methyl-8-nitroquinoline (CAS 65745-69-9), molecular formula C10H8N2O2 and molecular weight 188.18 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 5-Methyl-8-nitroquinoline (C10H8N2O2) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C10H8N2O2 |
| Molecular Weight | 188.18 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1975 |
| Nitrogen Atoms | 2 |
Related Methyl Standards
- 3-Methyl-5-nitroquinoline (CAS 103754-53-6)
- 8-Methyl-6-nitroquinoline (CAS 116529-86-3)
- 8-Methyl-7-nitroquinoline (CAS 168770-38-5)
- 4-Methyl-7-nitroquinoline (CAS 1823937-84-3)
- 2-Methyl-3-nitroquinoline (CAS 75353-77-4)
- 2-Methyl-5-nitroquinoline (CAS 23877-94-3)
- 2-Methyl-6-nitroquinoline (CAS 613-30-9)
- 2-Methyl-8-nitroquinoline (CAS 881-07-2)
Recommended Standards
- 5-Methyl-7-nitroquinoline (CAS 342043-94-1)
- 5-Nitro-1-naphthalenamine (CAS 3272-91-1)
- 5-Methyl-6-nitroquinoline (CAS 65745-70-2)
- 5-Nitronaphthalen-2-amine (CAS 607-44-3)
- 4-((1H-pyrazolo[3,4-b]pyridin-4-yl)oxy)-3-fluoroaniline (CAS 1115490-85-1)
- 4-(3-Chlorophenyl)piperidine (CAS 99329-53-0)
- 4-Chloro-1H-indazole-3,6-diol (CAS 887570-67-4)
- Menaquinone Impurity 46 (CAS 57766-68-4)
- 3-(2,3-Dichlorophenyl)propiolic acid (CAS 1342452-23-6)
- N-(3-Fluorobenzyl)-1-methyl-1H-pyrazol-3-amine hydrochloride (CAS 1855951-00-6)
- (E)-3-methoxy-3-oxoprop-1-en-1-yl 4-(tert-butyl)benzoate (CAS 478046-88-7)
- Diethyl Quinoline-2,3-dicarboxylate (CAS 32413-08-4)
- JWH-080 (CAS 210179-44-5)
- Tirzepatide Impurity 1 (CAS 2460751-66-8)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com