Phenyl (2-chloro-6,7,8-trimethoxyquinazolin-4-yl)carbamate CAS 65962-96-1
| CAS No. | 65962-96-1 |
| Molecular Formula | C18H16ClN3O5 |
| Molecular Weight | 389.79 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Phenyl (2-chloro-6,7,8-trimethoxyquinazolin-4-yl)carbamate.
Phenyl (2-chloro-6,7,8-trimethoxyquinazolin-4-yl)carbamate (CAS 65962-96-1), molecular formula C18H16ClN3O5 and molecular weight 389.79 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of Phenyl (2-chloro-6,7,8-trimethoxyquinazolin-4-yl)carbamate (C18H16ClN3O5) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures Phenyl (2-chloro-6,7,8-trimethoxyquinazolin-4-yl)carbamate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H16ClN3O5 |
| Molecular Weight | 389.79 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1975 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Phenyl Standards
- 2-Chloro-5-((6-methoxy-7-(2-methoxyethoxy)quinazolin-4-yl)amino)cyclohexa-2,5-diene-1,4-dione (CAS 870959-62-9)
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- (4-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)piperazin-1-yl)(3-methylthiophen-2-yl)methanone (CAS 1024338-68-8)
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Recommended Standards
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- Ethyl 2-((2-(4-chlorophenyl)-6-nitro-1H-benzo[d]imidazol-1-yl)oxy)propanoate (CAS 282523-41-5)
- 4-[({5-[(4-Chlorophenoxy)methyl]-1,3,4-thiadiazol-2-yl}carbonyl)amino]benzoic acid (CAS 1142202-91-2)
- 2-(4-Fluoro-2-propoxyphenyl)ethan-1-ol (CAS 1378467-36-7)
- 4-Fluoro-7-iodo-1H-indazole (CAS 1000341-76-3)
- 3-(3,4-Dimethylphenyl)prop-2-yn-1-ol (CAS 26801-34-3)
- 2-(3-Butoxy-4-fluorophenyl)ethan-1-ol (CAS 1443354-82-2)
- 2-Bromo-3-(trifluoromethyl)benzonitrile (CAS 914637-07-3)
- (S)-4-Oxo-1,2,3,4-tetrahydronaphthalene-2-carboxylic acid (CAS 113867-24-6)
- 4-Bromo-2-fluoro-3-(trifluoromethyl)benzoic acid (CAS 194804-96-1)
- 2-(Difluoromethyl)-4-fluoro-5-(trifluoromethyl)pyridine-3-acetic acid (CAS 1805446-69-8)
- Methyl 2-(benzyloxy)-4-methylbenzoate (CAS 424791-15-1)
- (DTyr27,36,DThr32)-Neuropeptide Y (27-36) (CAS 163887-48-7)
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