4-Chloro-1-(3-nitrophenyl)-1H-pyrazolo[3,4-d]pyrimidine CAS 65974-01-8
| CAS No. | 65974-01-8 |
| Molecular Formula | C11H6ClN5O2 |
| Molecular Weight | 275.65 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 4-Chloro-1-(3-nitrophenyl)-1H-pyrazolo[3,4-d]pyrimidine (CAS 65974-01-8), a certified reference material (molecular formula C11H6ClN5O2, MW 275.65 g/mol) for analytical method development and quality control.
The molecular framework of 4-Chloro-1-(3-nitrophenyl)-1H-pyrazolo[3,4-d]pyrimidine (C11H6ClN5O2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H6ClN5O2 |
| Molecular Weight | 275.65 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1975 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 5 |
Related Chloro Standards
- 2-Chloro-n-{3-[3-(trifluoromethyl)phenyl]prop-2-yn-1-yl}acetamide (CAS 1334148-02-5)
- 5-Chloro-2-[(3-nitropyridin-2-yl)oxy]benzonitrile (CAS 1417566-32-5)
- 2-Chloro-6-(3-nitrophenyl)-9H-purine (CAS 918537-04-9)
- 4-Chloro-1-(4-nitrophenyl)-1H-pyrazolo[3,4-d]pyrimidine (CAS 23000-49-9)
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Recommended Standards
- 4-(Chloromethyl)-5-methyl-2-(3-(trifluoromethyl)phenyl)oxazole (CAS 678164-78-8)
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- n-Hexadecyl-d33 Alcohol (CAS 284474-73-3)
- 4-Chloro-1-(3-(trifluoromethyl)benzyl)-1,2-dihydro-3h-pyrazol-3-imine (CAS 1004452-00-9)
- 3-(2,6-Dichlorophenyl)-4,4,4-trifluorobutanoic acid (CAS 1465010-43-8)
- Lithium-manganese dioxide (CAS 12162-79-7)
- 5-(Isoxazol-3-yl)-1,2,4-oxadiazole-3-carboxylic acid (CAS 1343426-68-5)
- 3-Amino-N-mesityl-4-methoxybenzamide (CAS 1016694-77-1)
- 3-Ethoxy-2-fluorobenzaldehyde (CAS 1204176-29-3)
- 1-Boc-3-methylpiperidine-4-carbaldehyde (CAS 512822-18-3)
- 4-(2-Amino-6-chloropyrimidin-4-yl)butanoic acid (CAS 688782-59-4)
- Ethanesulfonic anhydride (CAS 13223-06-8)
- 1-(3,5-Dimethoxyphenyl)propan-2-one (CAS 18917-77-6)
- D-Ala18-Tirzepatide (CAS CATO-CPTD788916)
Why CATO?
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