4-(Chloromethyl)-5-methyl-2-(3-(trifluoromethyl)phenyl)oxazole CAS 678164-78-8
| CAS No. | 678164-78-8 |
| Molecular Formula | C12H9ClF3NO |
| Molecular Weight | 275.65 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies 4-(Chloromethyl)-5-methyl-2-(3-(trifluoromethyl)phenyl)oxazole (CAS 678164-78-8), a certified reference material (molecular formula C12H9ClF3NO, MW 275.65 g/mol) for analytical method development and quality control.
Based on its molecular formula C12H9ClF3NO, 4-(Chloromethyl)-5-methyl-2-(3-(trifluoromethyl)phenyl)oxazole contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 275.65 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H9ClF3NO |
| Molecular Weight | 275.65 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloromethyl Standards
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- 2-(chloromethyl)-5-(5-methyl-3-phenylisoxazol-4-yl)-1,3,4-oxadiazole (CAS 63002-59-5)
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Recommended Standards
- 2-Chloro-6-(3-nitrophenyl)-9H-purine (CAS 918537-04-9)
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- 2-(4-TRIFLUOROMETHYLPHENYL)-4-CHLOROMETHYL-5-METHYLOXAZOLE (CAS 174258-39-0)
- 4-Chloro-1-(4-nitrophenyl)-1H-pyrazolo[3,4-d]pyrimidine (CAS 23000-49-9)
- tert-Butyl 4-[6-(5-chlorothiophen-2-yl)-3-cyanopyridin-2-yl]-1,4-diazepane-1-carboxylate (CAS 1198278-10-2)
- 2-Fluoro-2-methylpropyl trifluoromethanesulfonate (CAS 145349-17-3)
- 4-(3-Chloro-5-trifluoromethyl-pyridin-2-yl)-pyrimidine-2-thiol (CAS 1311278-19-9)
- Ethyl 4-bromo-2-fluoro-3-methylbenzoate (CAS 1394003-97-4)
- 4-Chloro-1,3-dimethyl-1h-pyrazole-5-sulfonyl chloride (CAS 88398-87-2)
- 4-(1-Pyrrolidinylmethyl)-1,3-thiazol-2-ylamine (CAS 17386-09-3)
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- Saxagliptin Impurity 29 (CAS 1496712-39-0)
- 2-[2-(4-chlorophenoxy)acetamido]benzoic acid (CAS 69764-09-6)
- Tirzepatide Impurity 18 (CAS CATO-C4X-324018)
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