1,3-Bis(trifluoromethoxy)benzene CAS 660-31-1
| CAS No. | 660-31-1 |
| Molecular Formula | C8H4F6O2 |
| Molecular Weight | 246.11 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 246.11 g/mol gives 1,3-Bis(trifluoromethoxy)benzene distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies 1,3-Bis(trifluoromethoxy)benzene (CAS 660-31-1), a certified reference material (molecular formula C8H4F6O2, MW 246.11 g/mol) for analytical method development and quality control.
1,3-Bis(trifluoromethoxy)benzene (C8H4F6O2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 1,3-Bis(trifluoromethoxy)benzene meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H4F6O2 |
| Molecular Weight | 246.11 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
Related Bis Standards
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- 2-[2-(trifluoromethoxy)phenyl]cyclopropane-1-carboxylic acid (CAS 1157562-08-7)
Recommended Standards
- 1-(4-(4,4,6-Trimethyl-1,3,2-dioxaborinan-2-yl)phenyl)ethan-1-one (CAS 934558-34-6)
- 1,4-Bis(trifluoromethyl)-2,5-dihydroxybenzene (CAS 203579-41-3)
- 1-(3,5-Bis(trifluoromethyl)-1H-pyrazol-1-yl)ethan-1-one (CAS 244187-01-7)
- 1,5-Dimethyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrole-2-carbonitrile (CAS 863868-49-9)
- 2767-91-1 4-(4-Pyridyl)morpholine 4-Morpholinopyridine P1646 (CAS 2767-91-1)
- 1,3-Dihydrobenzo[c]thiophene-5-carbonitrile 2,2-dioxide (CAS 76768-81-5)
- 1-(2-Chloro-6-fluorobenzyl)-1H-indole-3-carboxylic acid (CAS 1226365-40-7)
- 1-(4-(2-Chloro-6-methylpyrimidin-4-yl)piperazin-1-yl)ethan-1-one (CAS 1470523-33-1)
- 2,4-Dibromo-N-methylaniline (CAS 73557-58-1)
- 4-Hydroxy-6-methyl-2-oxo-1,2-dihydropyridine-3-carboxylic acid (CAS 846557-80-0)
- 4-Chloro-6-isopropyl-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine (CAS 1355195-24-2)
- rel-tert-Butyl ((1R,3R)-3-hydroxy-3-methylcyclopentyl)carbamate (CAS 1352343-66-8)
- 3-(4-Chlorobenzenesulfonyl)-N-[(1E)-(dimethylamino)methylidene]-5-(trifluoromethyl)pyridine-2-carboxamide (CAS 338407-02-6)
- Dendroaspis Natriuretic Peptide (CAS 255721-52-9)
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