1,4-Bis(trifluoromethyl)-2,5-dihydroxybenzene CAS 203579-41-3
| CAS No. | 203579-41-3 |
| Molecular Formula | C8H4F6O2 |
| Molecular Weight | 246.11 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
1,4-Bis(trifluoromethyl)-2,5-dihydroxybenzene (C8H4F6O2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
1,4-Bis(trifluoromethyl)-2,5-dihydroxybenzene (CAS 203579-41-3), molecular formula C8H4F6O2 and molecular weight 246.11 g/mol, is a CATO reference standard with documented purity and traceability.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H4F6O2 |
| Molecular Weight | 246.11 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2015 |
| Halogen Content | F-containing |
Related Bis Standards
- 1,4-Bis(trifluoromethyl)-2,3-dihydroxybenzene (CAS 1805519-27-0)
- 1-(3,5-Bis(trifluoromethyl)-1H-pyrazol-1-yl)ethan-1-one (CAS 244187-01-7)
- 5-methyl-2-(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyrimidine-7-carboxylic acid (CAS 1038261-10-7)
- 7-Methyl-2-trifluoromethyl-[1,2,4]triazolo[1,5-a]-pyrimidine-6-carboxylic acid (CAS 924846-75-3)
- Methyl 7-(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyrimidine-2-carboxylate (CAS 473994-46-6)
- N-(5-(Trifluoromethyl)-1H-1,2,4-triazol-3-yl)furan-2-carboxamide (CAS 499227-55-3)
- 2,5-Bis(trifluoromethyl)benzenethiol (CAS 1028328-58-6)
- (R)-6-(Trifluoromethyl)chromane-3-carboxylic acid (CAS 1260603-28-8)
Recommended Standards
- 1,3-Bis(trifluoromethoxy)benzene (CAS 660-31-1)
- 1,5-Dimethyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrole-2-carbonitrile (CAS 863868-49-9)
- 1-(4-(4,4,6-Trimethyl-1,3,2-dioxaborinan-2-yl)phenyl)ethan-1-one (CAS 934558-34-6)
- 1,5-Dimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrole-2-carbonitrile (CAS 863868-51-3)
- Methyl 2,4-difluoro-3-methoxyphenylacetate (CAS 1803729-77-2)
- 3-chloro-5-(2,4-dichlorophenyl)-4-methyl-4H-1,2,4-triazole (CAS 162693-32-5)
- 5-(Isobutylthio)-1,3,4-thiadiazole-2-thiol (CAS 89601-20-7)
- 1-(4-Bromophenyl)-2,3-butadien-1-one (CAS 378186-96-0)
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