Methyl(3,3,3-trifluoropropyl)silanediol CAS 660-78-6

Purity 97%+In StockPharmaceutical Standards
CAS No.660-78-6
Molecular FormulaC22H18Cl4O2
Molecular Weight456.19 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

Methyl(3,3,3-trifluoropropyl)silanediol CAS 660-78-6 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 456.19 g/mol gives Methyl(3,3,3-trifluoropropyl)silanediol distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

CATO supplies Methyl(3,3,3-trifluoropropyl)silanediol (CAS 660-78-6), a certified reference material (molecular formula C22H18Cl4O2, MW 456.19 g/mol) for analytical method development and quality control.

Owing to a steroid core, a hydroxyl group, an ether linkage, chlorine substitution, Methyl(3,3,3-trifluoropropyl)silanediol is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 456.19 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC22H18Cl4O2
Molecular Weight456.19 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at room temperature, protect from light
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)12.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1957
Halogen ContentCl-containing

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