GDC-0623 (5-((2-Fluoro-4-Iodophenyl)amino)-N-(2-Hydroxyethoxy)imidazo[1,5-a]pyridine-6-Carboxamide) CAS 1168091-68-6
| CAS No. | 1168091-68-6 |
| Molecular Formula | C16H14FIN4O3 |
| Molecular Weight | 456.21 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
GDC-0623 (5-((2-Fluoro-4-Iodophenyl)amino)-N-(2-Hydroxyethoxy)imidazo[1,5-a]pyridine-6-Carboxamide) (CAS 1168091-68-6) is a high-purity analytical reference standard with the molecular formula C16H14FIN4O3 and a molecular weight of 456.21 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/iodine substitution, GDC-0623 (5-((2-Fluoro-4-Iodophenyl)amino)-N-(2-Hydroxyethoxy)imidazo[1,5-a]pyridine-6-Carboxamide) is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 456.21 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a certified reference material (CRM), GDC-0623 (5-((2-Fluoro-4-Iodophenyl)amino)-N-(2-Hydroxyethoxy)imidazo[1,5-a]pyridine-6-Carboxamide) meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H14FIN4O3 |
| Molecular Weight | 456.21 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F/I-containing |
| Nitrogen Atoms | 4 |
Related GDC Standards
- N-(4-Fluoro-3-(2-methoxyethyl)benzo[d]thiazol-2(3H)-ylidene)-2-iodobenzamide (CAS 865248-73-3)
- (11β)-9-Fluoro-11,17-dihydroxy-21-[(methylsulfonyl)oxy]pregna-1,4-diene-3,20-dione (CAS 382-66-1)
- 2-(3-(2-((3-Fluoro-4-(4-methylpiperazin-1-yl)phenyl)amino)-5-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)phenyl)acetonitrile (CAS 1239875-86-5)
- 4-(3-Fluoro-4-methoxybenzoyl)-3-hydroxy-1-(3-morpholinopropyl)-5-(pyridin-4-yl)-1H-pyrrol-2(5H)-one (CAS 618073-02-2)
- 2-(5-Fluoro-3-(4-((4-fluorophenyl)sulfonyl)benzyl)-2-methyl-1H-indol-1-yl)acetic acid (CAS 1161864-21-6)
- 2-(4-Fluoro-phenyl)-4,4-dimethoxy-1-[4-(4-trifluoromethyl-pyridin-2-yl)-piperazin-1-yl]-butan-1-one (CAS 1227268-99-6)
- 5-Fluoro-1-(4-fluorobenzyl)pyrimidine-2,4(1H,3H)-dione (CAS 86547-17-3)
- 4-(3-Fluoro-4-methoxybenzoyl)-3-hydroxy-1-(3-morpholinopropyl)-5-phenyl-1H-pyrrol-2(5H)-one (CAS 609796-29-4)
Recommended Standards
- 2,6-Bis(2-chlorophenyl) 4-(trifluoromethyl)pyridine-2,6-dicarboxylate (CAS 1209764-28-2)
- 1,8-Bis(4-bromophenoxy)octane (CAS 117499-25-9)
- Methyl(3,3,3-trifluoropropyl)silanediol (CAS 660-78-6)
- 2-Bromo-4-(3-bromo-5-tert-butyl-4-hydroxyphenyl)-6-tert-butylphenol (CAS 60803-31-8)
- 2-Chloro-1-fluoro-4-(2-methylallyl)benzene (CAS 951888-17-8)
- N-(Furan-2-ylmethyl)-3-(6-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)propanamide (CAS 1105202-00-3)
- 2-Methyl-2-thiopseudourea hemisulfate (CAS 867-44-7)
- 2,4-Dihydroxy-3-(trifluoromethyl)pyridine (CAS 1227565-49-2)
- n'-Hydroxy-2-(oxan-4-yloxy)ethanimidamide (CAS 1251518-82-7)
- D-Leu26-Tirzepatide (CAS CATO-CPTD788908)
- 3-Amino-2-((tetrahydro-2h-pyran-4-yl)methyl)propanoic acid (CAS 1250243-02-7)
- tert-Butyl 3-(methoxymethyl)piperidine-3-carboxylate (CAS 2137647-95-9)
- 2,2,2-Trifluoro-1-(4-nitrophenyl)ethanamine (CAS 1270543-98-0)
- Liraglutide-d8 Tetratrifluoroacetate (CAS 204656-20-2 (non-labelled, free base))
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