2-Thiophenecarbonyl chloride CAS 66039-95-0
| CAS No. | 66039-95-0 |
| Molecular Formula | C5H2Cl2OS |
| Molecular Weight | 181.04 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-Thiophenecarbonyl chloride.
2-Thiophenecarbonyl chloride (CAS 66039-95-0), molecular formula C5H2Cl2OS and molecular weight 181.04 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2-Thiophenecarbonyl chloride (C5H2Cl2OS) is characterized by sulfur-containing functionality, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 2-Thiophenecarbonyl chloride under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C5H2Cl2OS |
| Molecular Weight | 181.04 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1975 |
| Halogen Content | Cl-containing |
| Sulfur Atoms | 1 |
Related Thiophenecarbonyl Standards
Recommended Standards
- 4,5-Dichlorothiophene-3-carbaldehyde (CAS 61200-59-7)
- 3-Chloro-2-thiophenecarbonyl chloride (CAS 86427-02-3)
- 3,5-Dichlorothiophene-2-carbaldehyde (CAS 67482-51-3)
- 2-Chloro-3-thiophenecarbonyl chloride (CAS 332370-74-8)
- 5-methyltryptamine hydrochloride (CAS 1010-95-3)
- 4-(Chloromethyl)-2-methyloxazole (CAS 141399-53-3)
- (3-amino-4-chloro-1H-pyrazol-1-yl)acetic acid,2HCl (CAS 1431968-09-0)
- 3-(Bromomethyl)-2-nitrobenzoic acid (CAS 920760-14-1)
- 5-Chloro-3,3-bis(4-hydroxyphenyl)indolin-2-one (CAS 861070-76-0)
- 3-(Pyrrolidin-2-yl)-4H-benzo[e][1,2,4]thiadiazine 1,1-dioxide hydrochloride (CAS 1956328-17-8)
- 3,6-Dichloro-4-((2-chloroethyl)thio)pyridazine (CAS 7152-70-7)
- 7-Methyl-1-(prop-2-yn-1-yl)indoline-2,3-dione (CAS 63725-92-8)
- Dimethyl 3-(3-chlorophenoxy)-2-oxopropylphosphonate (CAS 40665-94-9)
- Akt/SKG Substrate Peptide (CAS 276680-69-4)
Why CATO?
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