1-(2,4-Difluorophenyl)biguanide hydrochloride CAS 66088-52-6
| CAS No. | 66088-52-6 |
| Molecular Formula | C8H9F2N5 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
1-(2,4-Difluorophenyl)biguanide hydrochloride (CAS 66088-52-6) is a high-purity analytical reference standard with the molecular formula C8H9F2N5HCl and a molecular weight of 249.65 g/mol.
1-(2,4-Difluorophenyl)biguanide hydrochloride (C8H9F2N5HCl) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 1-(2,4-Difluorophenyl)biguanide hydrochloride under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H9F2N5 HCl |
| Molecular Weight | 249.65 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1975 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 5 |
Related Difluorophenyl Standards
- 1-(1-(2,6-Difluorophenyl)-5-methyl-1H-1,2,4-triazol-3-yl)ethanone (CAS 1000572-09-7)
- (2,4-Difluorophenyl)methanesulfonamide (CAS 1001026-56-7)
- Methyl 2-(2,3-difluorophenyl)-2-hydroxyacetate (CAS 1001159-03-0)
- 2-(2,4-Difluorophenyl)cyclopropan-1-amine (CAS 1001318-18-8)
- (4R)-4-(2,4-difluorophenyl)pyrrolidine-3-carbonitrile (CAS 1002728-74-6)
- N-(2,5-Difluorophenyl)-3-methylbenzamide (CAS 1002813-62-8)
- 4-(3,5-Difluorophenyl)piperidinehydrochloride (CAS 1004618-89-6)
- 4-(2,3-difluorophenyl)piperidine hydrochloride (CAS 1004618-90-9)
Recommended Standards
- 3-(Pentylamino)propanoic Acid (CAS 205237-07-6)
- 5-Fluoro-2-hydrazino-benzoicacid;hydrochloride (CAS 69196-09-4)
- 2-(4-Formyl-2-methoxyphenoxy)-N-(1-phenylethyl)acetamide (CAS 491581-46-5)
- 3,3′,5,5′-Tetracarboxydiphenylmethane (CAS 10397-52-1)
- 5-Oxospiro[2.3]hexane-1-carboxylic acid (CAS 1514428-20-6)
- (4-Chlorophenyl)hydrazine hemisulfate (CAS 14581-21-6)
- 2-Chloro-8-fluoro-6,7-dimethoxyquinazolin-4-amine (CAS 1515883-78-9)
- 2-(2-Bromo-4-chlorophenyl)-N-methylacetamide (CAS 1383543-19-8)
- tert-butyl N-{[3-(hydroxymethyl)oxetan-3-yl]methyl}carbamate (CAS 1393441-68-3)
- Semaglutide Impurity 142 (CAS CATO-C4X-2226142)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com