1-(2,5-DIfluorophenyl)biguanide hydrochloride CAS 66088-53-7
| CAS No. | 66088-53-7 |
| Molecular Formula | C8H9F2N5 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 249.65 g/mol gives 1-(2,5-DIfluorophenyl)biguanide hydrochloride distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
1-(2,5-DIfluorophenyl)biguanide hydrochloride (CAS 66088-53-7), molecular formula C8H9F2N5HCl and molecular weight 249.65 g/mol, is a CATO reference standard with documented purity and traceability.
Based on its molecular formula C8H9F2N5HCl, 1-(2,5-DIfluorophenyl)biguanide hydrochloride contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 249.65 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H9F2N5 HCl |
| Molecular Weight | 249.65 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1975 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 5 |
Related DIfluorophenyl Standards
- 1-(1-(2,6-Difluorophenyl)-5-methyl-1H-1,2,4-triazol-3-yl)ethanone (CAS 1000572-09-7)
- (2,4-Difluorophenyl)methanesulfonamide (CAS 1001026-56-7)
- Methyl 2-(2,3-difluorophenyl)-2-hydroxyacetate (CAS 1001159-03-0)
- 2-(2,4-Difluorophenyl)cyclopropan-1-amine (CAS 1001318-18-8)
- (4R)-4-(2,4-difluorophenyl)pyrrolidine-3-carbonitrile (CAS 1002728-74-6)
- N-(2,5-Difluorophenyl)-3-methylbenzamide (CAS 1002813-62-8)
- 4-(3,5-Difluorophenyl)piperidinehydrochloride (CAS 1004618-89-6)
- 4-(2,3-difluorophenyl)piperidine hydrochloride (CAS 1004618-90-9)
Recommended Standards
- ANtifungal agent 1 (CAS 1265166-14-0)
- 4-Fluoro-2-methyl-piperidine (CAS 1638920-44-1)
- 5-Bromo-1H-benzimidazol-2-yl methyl sulfide (CAS 303140-06-9)
- 6-Bromo-1-methyl-1H-pyrazolo[3,4-b]pyridine (CAS 1289261-71-7)
- Ethyl 3-(2-methylpropyl)-1,2,4-oxadiazole-5-carboxylate (CAS 1389315-06-3)
- 4-(Azetidin-1-yl)piperidine (CAS 686298-29-3)
- 4-(Aminomethyl)-2-cyano-6-(difluoromethoxy)benzoic acid (CAS 1805587-07-8)
- (E)-3-(2-Cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl)acrylonitrile (CAS 256431-72-8)
- 2-{[(tert-butoxy)carbonyl]amino}-3-(1,3-thiazol-2-yl)propanoic acid (CAS 879502-02-0)
- Semaglutide impurity 56 (CAS CATO-C4X-222656)
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