Valaciclovir EP Impurity A CAS 66224-64-4

Purity 97%+In StockPharmacopoeial Impurity Standards
CAS No.66224-64-4
Molecular FormulaC5H5N5O
Molecular Weight151.13 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Valaciclovir EP Impurity A CAS 66224-64-4 chemical structure

Description

Structurally, Valaciclovir EP Impurity A (C5H5N5O) contains an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 6.0, corresponding to approximately 6 ring(s) or double-bond equivalent(s). With a molecular weight of 151.13 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

Valaciclovir EP Impurity A (CAS 66224-64-4) is a certified pharmaceutical impurity reference standard with the molecular formula C5H5N5O and a molecular weight of 151.13 g/mol.

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

As a certified reference material (CRM), Valaciclovir EP Impurity A meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC5H5N5O
Molecular Weight151.13 g/mol
AppearanceOff-white to pale yellow crystalline powder. (faint amine-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityLight-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)6.0
UV AbsorptionUV-absorbing
CAS Registry Year (est.)1975
Nitrogen Atoms5

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