Ganciclovir EP Impurity F CAS 73-40-5

Purity >95%In StockPharmacopoeial Impurity Standards
CAS No.73-40-5
Molecular FormulaC5H5N5O
Molecular Weight151.13 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Ganciclovir EP Impurity F CAS 73-40-5 chemical structure

Description

Ganciclovir EP Impurity F (CAS 73-40-5) is a certified pharmaceutical impurity reference standard with the molecular formula C5H5N5O and a molecular weight of 151.13 g/mol.

The molecular framework of Ganciclovir EP Impurity F (C5H5N5O) is characterized by an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

As a certified reference material (CRM), Ganciclovir EP Impurity F meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC5H5N5O
Molecular Weight151.13 g/mol
AppearanceOff-white to pale yellow crystalline powder. (faint amine-like odor)
Purity>95%
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityLight-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)6.0
UV AbsorptionUV-absorbing
CAS Registry Year (est.)1957
Nitrogen Atoms5

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