2,8-Dibromo-4-(trifluoromethyl)quinoline-3-carboxylic acid CAS 663193-43-9
| CAS No. | 663193-43-9 |
| Molecular Formula | C11H4Br2F3NO2 |
| Molecular Weight | 398.96 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2,8-Dibromo-4-(trifluoromethyl)quinoline-3-carboxylic acid (CAS 663193-43-9), molecular formula C11H4Br2F3NO2 and molecular weight 398.96 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 2,8-Dibromo-4-(trifluoromethyl)quinoline-3-carboxylic acid (C11H4Br2F3NO2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/bromine substitution. The molecule exhibits a degree of unsaturation (DBE) of 8.0, corresponding to approximately 8 ring(s) or double-bond equivalent(s). With a molecular weight of 398.96 g/mol, it falls into the moderately-high-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2,8-Dibromo-4-(trifluoromethyl)quinoline-3-carboxylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H4Br2F3NO2 |
| Molecular Weight | 398.96 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 1 |
Related Dibromo Standards
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- 1-Methyl-2,3-dihydropyridin-4(1H)-one (CAS 35488-00-7)
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- 2-mercapto-3-(2-phenylethyl)-3,5,6,7-tetrahydro-4H-cyclopenta[4,5]thieno[2,3-d]pyrimidin-4-one (CAS 351005-68-0)
- (2,4-Dichlorophenoxy-d3)acetic-2,2-d2 Acid (CAS 352438-69-8)
- Sperm Activating Peptide, Sea Urchin (CAS 140653-27-6)
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