2-Bromo-8-chloro-4-(trifluoromethyl)quinoline-3-carboxylic acid CAS 663193-41-7
| CAS No. | 663193-41-7 |
| Molecular Formula | C11H4BrClF3NO2 |
| Molecular Weight | 354.51 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Structurally, 2-Bromo-8-chloro-4-(trifluoromethyl)quinoline-3-carboxylic acid (C11H4BrClF3NO2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine/bromine substitution. The molecule exhibits a degree of unsaturation (DBE) of 8.0, corresponding to approximately 8 ring(s) or double-bond equivalent(s). With a molecular weight of 354.51 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO supplies 2-Bromo-8-chloro-4-(trifluoromethyl)quinoline-3-carboxylic acid (CAS 663193-41-7), a certified reference material (molecular formula C11H4BrClF3NO2, MW 354.51 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2-Bromo-8-chloro-4-(trifluoromethyl)quinoline-3-carboxylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H4BrClF3NO2 |
| Molecular Weight | 354.51 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F/Cl/Br-containing |
| Nitrogen Atoms | 1 |
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Recommended Standards
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- 2,2'-Disulfanediylbis(N-methylethan-1-amine) (CAS 4747-27-7)
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- 3-(Furan-2-yl)-2-phenylisoxazolidin-5-ol (CAS 189255-05-8)
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- 2-Oxo-1,2-dihydroquinoline-7-carboxylic acid (CAS 320349-89-1)
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- 2-(4-Chlorophenyl)quinoxaline (CAS 17286-63-4)
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