4-Hydroxyquinazoline-8-carbonitrile CAS 663194-04-5
| CAS No. | 663194-04-5 |
| Molecular Formula | C9H5N3O |
| Molecular Weight | 171.16 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
CATO supplies 4-Hydroxyquinazoline-8-carbonitrile (CAS 663194-04-5), a certified reference material (molecular formula C9H5N3O, MW 171.16 g/mol) for analytical method development and quality control.
Structurally, 4-Hydroxyquinazoline-8-carbonitrile (C9H5N3O) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 9.0, corresponding to approximately 9 ring(s) or double-bond equivalent(s). With a molecular weight of 171.16 g/mol, it falls into the medium-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C9H5N3O |
| Molecular Weight | 171.16 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Nitrogen Atoms | 3 |
Related Hydroxyquinazoline Standards
- 6-Hydroxyquinazoline-4-carbonitrile (CAS 1823902-39-1)
- 7-Hydroxyquinazoline-2,4(1H,3H)-dione (CAS 861546-03-4)
- 6-Hydroxyquinazoline-2,4(1H,3H)-dione (CAS 17730-74-4)
- 4-hydroxyquinazoline-2-carbaldehyde (CAS 104968-03-8)
- 4-hydroxyquinazoline-6-carbaldehyde (CAS 1121529-15-4)
- 4-Hydroxyquinazoline-7-carboxamide (CAS 954803-07-7)
- 2-Hydroxyquinazoline-4-carboxylic acid (CAS 99066-77-0)
- Ethyl 2-hydroxyquinazoline-4-carboxylate (CAS 1141669-83-1)
Recommended Standards
- 4-Hydroxy-1,5-naphthyridine-3-carbonitrile (CAS 305371-00-0)
- 4-Oxo-3,4-dihydrophthalazine-1-carbonitrile (CAS 7694-84-0)
- 4-Amino-N-(2-aminoethyl)-1,2,5-oxadiazole-3-carboxamide (CAS 329922-36-3)
- 5-(Pyridin-3-yl)-1h-1,2,3-triazole-4-carbonitrile (CAS 884504-69-2)
- Ticagrelor metabolite-M8 D7 (CAS 220347-05-7 (unlabelled))
- 5-Chloro-2,3-difluoro-4-iodo-pyridine (CAS 406676-26-4)
- (3-Bromo-4-(2,2-difluoroethoxy)phenyl)methanol (CAS 1340151-27-0)
- 1-(Pyrrolidin-3-yl)cyclopropanamine (CAS 107286-29-3)
- 2-(2-Bromo-6-(trifluoromethyl)phenyl)acetonitrile (CAS 1159512-49-8)
- 6-Iodo-8-nitroquinoline (CAS 5552-46-5)
- 1-(3-Chloro-4-methylphenyl)-2-methylpropan-2-ol (CAS 1314965-00-8)
- 5,6-Dimethyl-2-(4-(piperidin-1-yl)phenyl)-3a,4,7,7a-tetrahydro-1H-isoindole-1,3(2H)-dione (CAS 302804-44-0)
- 2-(1H-Benzo[d]imidazol-1-yl)benzoic acid (CAS 29003-05-2)
- Semaglutide impurity 34 (CAS CATO-C4X-222634)
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