2-(Methylamino)-2-(p-tolyl)acetic acid hydrochloride CAS 66380-03-8
| CAS No. | 66380-03-8 |
| Molecular Formula | C10H13NO2 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 2-(Methylamino)-2-(p-tolyl)acetic acid hydrochloride (CAS 66380-03-8), a certified reference material (molecular formula C10H13NO2HCl, MW 215.68 g/mol) for analytical method development and quality control.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, 2-(Methylamino)-2-(p-tolyl)acetic acid hydrochloride is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 215.68 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 2-(Methylamino)-2-(p-tolyl)acetic acid hydrochloride under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H13NO2 HCl |
| Molecular Weight | 215.68 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1975 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Methylamino Standards
- 4-(Methylamino)phenyl furan-2-carboxylate (CAS 100063-33-0)
- 2-(methylamino)-6,7-dihydro-3H-purin-6-one (CAS 10030-78-1)
- 6-(Methylamino)pyridine-3-boronic Acid Pinacol Ester (CAS 1005009-98-2)
- 2-(Methylamino)cyclopentan-1-ol (CAS 100524-01-4)
- 2-(Methylamino)ethane-1-thiol (CAS 10061-40-2)
- 1-(2-(Methylamino)-2-oxoethyl)-1H-pyrazole-3-carboxylic acid (CAS 1006463-30-4)
- Ethyl 4-((methylamino)methyl)benzoate hydrochloride (CAS 1007870-76-9)
- 2-methyl-2-(methylamino)-1-phenyl-propan-1-ol (CAS 10079-55-7)
Recommended Standards
- ethyl 2-acetamido-3-oxobutanoate (CAS 5431-93-6)
- 1-(4-Chloro-3,5-difluorophenyl)ethan-1-one (CAS 1256352-85-8)
- 2-(2-Aminoethyl)pyrimidin-4-ol (CAS 944898-56-0)
- (2E)-3-[4-(Benzyloxy)phenyl]-1-(3,4-dichlorophenyl)prop-2-en-1-one (CAS 1354941-20-0)
- 9-Benzyl-N,N-diethyl-9H-purin-6-amine (CAS 64456-05-9)
- Methothrin (CAS 34388-29-9)
- Furan-3-yl(4-methoxyphenyl)methanol (CAS 1249553-63-6)
- N-(2-MEthoxyethyl)-6-piperidin-4-ylnicotinamide dihydrochloride (CAS 1858250-13-1)
- Dapoxetine Impurity 99 (CAS CATO-C4X-143999)
- Macrocyclic Peptide flaviviridae Viruses InhibitorDISCONTINUED (CAS 1510841-23-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com