1,3,5-Tris[4-(chloromethyl)phenyl]benzene CAS 66449-09-0
| CAS No. | 66449-09-0 |
| Molecular Formula | C27H21Cl3 |
| Molecular Weight | 451.81 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
1,3,5-Tris[4-(chloromethyl)phenyl]benzene (CAS 66449-09-0), molecular formula C27H21Cl3 and molecular weight 451.81 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 1,3,5-Tris[4-(chloromethyl)phenyl]benzene (C27H21Cl3) is characterized by chlorine substitution, a polycyclic aromatic system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO manufactures 1,3,5-Tris[4-(chloromethyl)phenyl]benzene under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C27H21Cl3 |
| Molecular Weight | 451.81 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1975 |
| Halogen Content | Cl-containing |
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Recommended Standards
- 1-Benzyl-2-(prop-2-en-1-ylsulfanyl)-5-[(1E)-[2-(2,4,6-trichlorophenyl)hydrazin-1-ylidene]methyl]-1H-imidazole (CAS 477854-38-9)
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- N-Dodecylstearamide (CAS 50354-87-5)
- 1-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)piperidin-4-one O-(3-(trifluoromethyl)benzyl) oxime (CAS 250714-10-4)
- 2-(Difluoromethyl)-6-iodo-5-nitropyridine-3-carbonyl chloride (CAS 1804864-59-2)
- tert-Butyl 1-(2,6-difluorobenzyl)piperidin-4-ylcarbamate (CAS 1286272-65-8)
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Why CATO?
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