4-((4-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)oxy)phenyl)amino)-2-(dimethylamino)-6-oxo-6H-1,3-oxazine-5-carbonitrile CAS 337920-37-3
| CAS No. | 337920-37-3 |
| Molecular Formula | C19H13ClF3N5O3 |
| Molecular Weight | 451.79 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 451.79 g/mol gives 4-((4-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)oxy)phenyl)amino)-2-(dimethylamino)-6-oxo-6H-1,3-oxazine-5-carbonitrile distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
4-((4-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)oxy)phenyl)amino)-2-(dimethylamino)-6-oxo-6H-1,3-oxazine-5-carbonitrile (CAS 337920-37-3), molecular formula C19H13ClF3N5O3 and molecular weight 451.79 g/mol, is a CATO reference standard with documented purity and traceability.
Based on its molecular formula C19H13ClF3N5O3, 4-((4-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)oxy)phenyl)amino)-2-(dimethylamino)-6-oxo-6H-1,3-oxazine-5-carbonitrile contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 451.79 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 4-((4-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)oxy)phenyl)amino)-2-(dimethylamino)-6-oxo-6H-1,3-oxazine-5-carbonitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C19H13ClF3N5O3 |
| Molecular Weight | 451.79 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 5 |
Related Chloro Standards
- 1-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)piperidin-4-one O-(3-(trifluoromethyl)benzyl) oxime (CAS 250714-10-4)
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- (3-(3-((2-Chloro-6-fluorobenzyl)oxy)phenyl)-1H-pyrazol-1-yl)(4-nitrophenyl)methanone (CAS 477712-56-4)
- 1-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)amino)-3-cyanopropan-2-yl 3-(trifluoromethyl)benzoate (CAS 339016-35-2)
- 2-((4-Chloro-N-(2,4-dichloro-5-methoxyphenyl)phenyl)sulfonamido)-N,N-dimethylacetamide (CAS 338961-60-7)
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Recommended Standards
- 1-Benzyl-2-(prop-2-en-1-ylsulfanyl)-5-[(1E)-[2-(2,4,6-trichlorophenyl)hydrazin-1-ylidene]methyl]-1H-imidazole (CAS 477854-38-9)
- Sorafenib Impurity 16 (CAS 1012058-78-4)
- 1,3,5-Tris[4-(chloromethyl)phenyl]benzene (CAS 66449-09-0)
- 5-(Chloromethyl)-4-(4-(trifluoromethoxy)benzyl)-2-(4-(trifluoromethyl)phenyl)thiazole (CAS 444613-05-2)
- Pregomisin (CAS 66280-26-0)
- 1-Isobutyl-3-(pyrazin-2-yl)-1H-pyrazole-4-carbaldehyde (CAS 1409686-48-1)
- NSC308848 (CAS 69408-82-8)
- Metronidazole EP Impurity E (CAS 705-19-1)
- (S)-3-(3-chlorophenyl)pyrrolidine (CAS 1335494-47-7)
- (4-Isopropoxy-5-methoxy-2-(methoxymethoxy)phenyl)boronic acid (CAS 875654-34-5)
- 2-(3-Amino-4-methoxyphenyl)-1λ6,2-thiazolidine-1,1-dione (CAS 927963-79-9)
- 3-Benzylidene-6-chloroindolin-2-one (CAS 387343-81-9)
- 1,4-Dichloroanthracene (CAS 66259-12-9)
- Cholecystokinin Octapeptide (sulfated) (H-2060.0005) (CAS 25679-23-6)
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