2-(4-Methylphenyl)butanedioic acid CAS 66483-40-7
| CAS No. | 66483-40-7 |
| Molecular Formula | C11H12O4 |
| Molecular Weight | 208.21 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 2-(4-Methylphenyl)butanedioic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
2-(4-Methylphenyl)butanedioic acid (CAS 66483-40-7) is a high-purity analytical reference standard with the molecular formula C11H12O4 and a molecular weight of 208.21 g/mol.
2-(4-Methylphenyl)butanedioic acid (C11H12O4) contains a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. It is notably hygroscopic, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C11H12O4 |
| Molecular Weight | 208.21 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1975 |
Related Methylphenyl Standards
- 2-(3-Methylphenyl)butanedioic acid (CAS 1195656-70-2)
- 2-{[(3-methylphenyl)carbamoyl]amino}acetic acid (CAS 133115-37-4)
- 2-[(2-methylphenyl)amino]benzonitrile (CAS 52577-72-7)
- 3-(4-methylphenyl)benzaldehyde (CAS 116470-54-3)
- 4-(2-Methylphenyl)-1,3-thiazole-2-thiol (CAS 189149-18-6)
- 4-(4-Methylphenyl)-1,3-thiazole-2-thiol (CAS 2103-92-6)
- Methyl 3-{[(3-methylphenyl)methyl]amino}propanoate (CAS 1094276-43-3)
- 2-[(4-Methylphenyl)amino]butanohydrazide (CAS 1163291-96-0)
Recommended Standards
- 2-(4-Methoxyphenyl)-2-oxoethyl acetate (CAS 58518-78-8)
- 2-(4-Nitrophenyl)morpholine (CAS 61192-65-2)
- 2-(4-Formylphenoxy)butanoic acid (CAS 480994-55-6)
- 2-(6-methoxy-2,3-dihydro-1-benzofuran-3-yl)acetic Acid (CAS 93198-72-2)
- 2H-1,2,3-Triazol-2-amine hydrochloride (CAS 1071586-37-2)
- 2-{6-[(benzyloxy)methoxy]-3-oxo-3H-xanthen-9-yl}benzoic acid (CAS 277309-46-3)
- Methyl 6-isopropyl-2-(4-(piperidin-1-ylsulfonyl)benzamido)-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylate (CAS 449768-00-7)
- Methyl 4-(bromomethyl)thiophene-3-carboxylate (CAS 99708-92-6)
- 2-(5-Bromo-1-benzofuran-2-yl)ethan-1-ol (CAS 460748-15-6)
- 2-Cyclopentylamino-5-methyl-3-nitropyridine (CAS 1033202-29-7)
- (1R,2S)-2-(3,4-dichlorobenzoyl)cyclohexane-1-carboxylic acid (CAS 844856-66-2)
- 2-(4-Chloro-3-fluorophenyl)piperidine (CAS 1257299-97-0)
- 6-Ethynyl-2-methyl-2H-indazole (CAS 2551117-88-3)
- Peptide Impurity 82 (CAS 10491-78-8)
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