4-Ethynyl-2-methylpiperidin-4-ol CAS 66493-36-5
| CAS No. | 66493-36-5 |
| Molecular Formula | C8H13NO |
| Molecular Weight | 139.19 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-Ethynyl-2-methylpiperidin-4-ol.
CATO supplies 4-Ethynyl-2-methylpiperidin-4-ol (CAS 66493-36-5), a certified reference material (molecular formula C8H13NO, MW 139.19 g/mol) for analytical method development and quality control.
The molecular framework of 4-Ethynyl-2-methylpiperidin-4-ol (C8H13NO) is characterized by an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H13NO |
| Molecular Weight | 139.19 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1975 |
| Nitrogen Atoms | 1 |
Related Ethynyl Standards
- 4-Ethynyl-1-methylpiperidin-4-ol (CAS 20734-46-7)
- 5-Ethynyl-2-methoxythiazole (CAS 1849269-96-0)
- 5-Ethynyl-3-methoxy-1,2-thiazole (CAS 1934419-21-2)
- 4-Ethynyl-3-methoxyisothiazole (CAS 2163673-46-7)
- 3-ethynyl-3-hydroxy-1-methylpyrrolidin-2-one (CAS 1202769-93-4)
- (R)-3-Ethynyl-3-hydroxy-1-methylpyrrolidin-2-one, >97% (CAS 1451089-77-2)
- (S)-3-Ethynyl-3-hydroxy-1-methylpyrrolidin-2-one (CAS 1799615-79-4)
- 2-Ethynyl-3,5-difluoropyridine (CAS 1121585-18-9)
Recommended Standards
- 4-Methyl-4-azaspiro[2.5]Octan-7-one (CAS 2060043-07-2)
- 4-ethyl-3-oxohexanenitrile (CAS 42124-67-4)
- 4-oxa-9-azatricyclo[5.3.0.0^{2,6}]decane (CAS 2059937-00-5)
- 4-Cyclobutylpyrrolidin-2-one (CAS 271579-94-3)
- tert-Butyl 3-(2-oxocyclobutyl)pyrrolidine-1-carboxylate (CAS 1823230-92-7)
- 2-Chloro-1-(4-(furan-2-ylmethyl)piperazin-1-yl)ethan-1-one (CAS 1183888-70-1)
- 7-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1,2,3,4-tetrahydroquinoline (CAS 1235142-07-0)
- 2,5-bis(chloromethyl)-1,3,4-oxadiazole (CAS 541540-90-3)
- Monopotassium 7-Amino-1,3-naphthalenedisulfonate Hydrate (CAS 842-15-9)
- (2-Amino-5-(difluoromethyl)-6-iodopyridin-3-yl)methanol (CAS 1806915-33-2)
- Epinastine Impurity 24 (CAS 1110929-19-5)
- cis-3-hydroxycyclohexanecarboxylic acid (CAS 22267-35-2)
- 3-(p-Tolyl)-2,5-dihydrofuran (CAS 859444-21-6)
- Semaglutide-d5 (CAS CATO-C4X-2226153)
Why CATO?
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