Galantamine EP Impurity D CAS 664995-65-7
| CAS No. | 664995-65-7 |
| Molecular Formula | C17H19NO2 |
| Molecular Weight | 269.34 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Galantamine EP Impurity D is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
As a process- or degradation-related impurity, Galantamine EP Impurity D (CAS 664995-65-7, C17H19NO2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, Galantamine EP Impurity D is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 269.34 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Galantamine EP Impurity D meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C17H19NO2 |
| Molecular Weight | 269.34 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | ≥95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Nitrogen Atoms | 1 |
Related Galantamine Standards
- Galantamine EP Impurity E (N-Desmethyl Galanthamine) (CAS 41303-74-6)
- Galantamine Impurity 6 (CAS 60755-80-8)
- Galantamine EP Impurity A (Galantaminone) (CAS 510-77-0)
- Galantamine Impurity 11 (CAS 21041-10-1)
- Galantamine EP Impurity B (CAS 1668-85-5)
- Galantamine EP Impurity F (ent-Galantamine) (CAS 60384-53-4)
- Galantamine EP Impurity C (CAS 21133-52-8)
- Galantamine-d6 (CAS 1128109-00-1)
Recommended Standards
- Pregabalin impurity 108 (CAS CATO-C4X-1312108)
- Galanthamine Impurity 40 (CAS 31504-42-4)
- Tamoxifen Impurity 26 (CAS CATO-C4X-123326)
- Ampicillin Impurity 74 (CAS CATO-C4X-144374)
- Oxiracetam Impurity 12 (CAS 88-00-6)
- Sulbactam EP Impurity D Potassium Salt (CAS 4027-64-9)
- Tizanidine impurity 18 (CAS 34658-84-9)
- Thiazolidine-2,4-dithione (CAS 4303-27-9)
- Piperidin-4-yl-pyridin-4-yl-amine x 2 HCl (CAS 181258-50-4)
- 1-(2-methoxyethyl)-1H-1,3-benzodiazol-2-amine (CAS 1038373-41-9)
- Cefazolin Impurity N14 (CAS 21743-64-6)
- 8-(2-Chlorobenzyl)-2,5-dimethyl-7,8-dihydro-6H-pyrazolo[1,5-a]pyrrolo[3,2-e]pyrimidine (CAS 860610-80-6)
- (S)-4-Amino-2-butanol (CAS 1255240-50-6)
- Des-Pro36-Tirzepatide (CAS CATO-CPTD788937)
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