Etomidate Impurity 8 CAS 66512-37-6
| CAS No. | 66512-37-6 |
| Molecular Formula | C12H17NO2 |
| Molecular Weight | 207.27 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Etomidate Impurity 8 (CAS 66512-37-6) is a certified pharmaceutical impurity reference standard with the molecular formula C12H17NO2 and a molecular weight of 207.27 g/mol.
Owing to an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage, Etomidate Impurity 8 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 207.27 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Etomidate Impurity 8 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H17NO2 |
| Molecular Weight | 207.27 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1976 |
| Nitrogen Atoms | 1 |
Related Etomidate Standards
- Etomidate Impurity 24 (CAS CATO-C4X-188424)
- Etomidate Impurity 15 (CAS CATO-C4X-188415)
- Etomidate Impurity 74 (CAS CATO-C4X-188474)
- Etomidate Impurity 72 (CAS CATO-C4X-188472)
- Etomidate impurity 63 (CAS CATO-C4X-188463)
- Etomidate Impurity 21 (CAS CATO-C4X-188421)
- Etomidate impurity 69 (CAS CATO-C4X-188469)
- Etomidate EP Impurity A (CAS 56649-48-0)
Recommended Standards
- Esmolol Impurity 60 (CAS CATO-C4X-189160)
- Lacosamide Impurity 43 (CAS 69805-82-9)
- Tetracaine EP Impurity C (CAS 71839-12-8)
- Indobufen Impurity 74 (CAS CATO-C4X-179274)
- Gliquidone Impurity 11 (CAS CATO-C4X-300011)
- Trospium Impurity 13 (CAS CATO-C4X-203813)
- Tofacitinib Impurity 221 (CAS CATO-C4X-1079221)
- 2-Chloro-4-fluoro-N-(2,2,2-trifluoroethyl)aniline (CAS 1038369-35-5)
- (S)-6-bromo-4-fluoro-2,3-dihydro-1H-inden-1-amine (CAS 1259809-68-1)
- [5-(1-Pyrrolidinylsulfonyl)-2-furyl]methanamine (CAS 887405-26-7)
- 1,3,6-Trihydroxy-2,5-dimethoxy-9H-xanthen-9-one (CAS 345287-92-5)
- 4-Benzyl-5-chloro-2-(methylthio)pyrimidine (CAS 118506-86-8)
- Benzo[lmn]benzo[4,5]imidazo[2,1-b]benzo[4,5]imidazo[1,2-j][3,8]phenanthroline-6,9-dione (CAS 4216-02-8)
- Semaglutide impurity 44 (CAS CATO-C4X-222644)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com