Etomidate EP Impurity A CAS 56649-48-0
| CAS No. | 56649-48-0 |
| Molecular Formula | C12H12N2O2 |
| Molecular Weight | 216.24 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Etomidate EP Impurity A under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Etomidate EP Impurity A (CAS 56649-48-0) is a certified pharmaceutical impurity reference standard with the molecular formula C12H12N2O2 and a molecular weight of 216.24 g/mol.
Etomidate EP Impurity A (C12H12N2O2) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C12H12N2O2 |
| Molecular Weight | 216.24 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1973 |
| Nitrogen Atoms | 2 |
Related Etomidate Standards
- Etomidate EP Impurity A (CAS 7036-56-8)
- (S)-Etomidate EP Impurity A (CAS 56649-49-1)
- Etomidate EP Impurity A (CAS 3157-27-5)
- Etomidate Impurity 17 (CAS 81591-23-3)
- Etomidate impurity 63 (CAS CATO-C4X-188463)
- Etomidate Impurity 72 (CAS CATO-C4X-188472)
- Etomidate Impurity 24 (CAS CATO-C4X-188424)
- Etomidate Impurity 8 (CAS 66512-37-6)
Recommended Standards
- Leflunomide EP Impurity G (CAS 724429-16-7)
- Leflunomide Impurity 25 (CAS CATO-C4X-167325)
- Famotidine impurity 71 (CAS 87855-83-2)
- Tryptophan EP Impurity H (CAS 6052-68-2)
- Warfarin impurity 15 (CAS CATO-C4X-17815)
- Capecitabine Impurity 53 (CAS CATO-C4X-102453)
- Nebivolol Impurity 36 (CAS 129101-33-3)
- Formoterol impurity 123 (CAS CATO-C4X-1525123)
- Methyl 2-(2,6-Dichlorobenzyl)oxazole-4-carboxylate (CAS 736971-94-1)
- Diethyl 9-ethoxynonylphosphonate (CAS 1052137-31-1)
- Hexadecyltrimethylammonium Bromide (CAS 57-09-0)
- N-(4-Methyl-5-thioxo-4,5-dihydro-1H-1,2,4-triazol-3-yl)acetamide (CAS 71521-92-1)
- 2-Acetamido-9H-purin-6-yl diphenylcarbamate (CAS 112233-74-6)
- Vasonatrin Peptide (VNP) trifluoroacetate salt (CAS 141676-35-9)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com