2-Chloro-3-(piperazin-1-yl)pyrazine hydrochloride CAS 66522-30-3

Purity 97%+In StockPharmaceutical Standards
CAS No.66522-30-3
Molecular FormulaC8H11ClN4
Molecular WeightN/A
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-Chloro-3-(piperazin-1-yl)pyrazine hydrochloride CAS 66522-30-3 chemical structure

Description

The occurrence of 2-Chloro-3-(piperazin-1-yl)pyrazine hydrochloride is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

2-Chloro-3-(piperazin-1-yl)pyrazine hydrochloride (CAS 66522-30-3), molecular formula C8H11ClN4HCl and molecular weight 235.11 g/mol, is a CATO reference standard with documented purity and traceability.

Structurally, 2-Chloro-3-(piperazin-1-yl)pyrazine hydrochloride (C8H11ClN4HCl) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 4.0, corresponding to approximately 4 ring(s) or double-bond equivalent(s). With a molecular weight of 235.11 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures 2-Chloro-3-(piperazin-1-yl)pyrazine hydrochloride under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC8H11ClN4 HCl
Molecular Weight235.11 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)4.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1976
Halogen ContentCl-containing
Nitrogen Atoms4

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