1-{[2-(2H-1,3-Benzodioxol-5-yl)imidazo[1,2-a]pyridin-3-yl]methyl}piperidine-3-carboxylic acid CAS 904816-43-9
| CAS No. | 904816-43-9 |
| Molecular Formula | C21H21N3O4 |
| Molecular Weight | 379.41 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 1-{[2-(2H-1,3-Benzodioxol-5-yl)imidazo[1,2-a]pyridin-3-yl]methyl}piperidine-3-carboxylic acid is closely related to a flavonoid core, an amide group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
1-{[2-(2H-1,3-Benzodioxol-5-yl)imidazo[1,2-a]pyridin-3-yl]methyl}piperidine-3-carboxylic acid (CAS 904816-43-9), molecular formula C21H21N3O4 and molecular weight 379.41 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, 1-{[2-(2H-1,3-Benzodioxol-5-yl)imidazo[1,2-a]pyridin-3-yl]methyl}piperidine-3-carboxylic acid is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 379.41 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C21H21N3O4 |
| Molecular Weight | 379.41 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Nitrogen Atoms | 3 |
Related H Standards
- 1-(2H-1,3-Benzodioxol-5-yl)-N-[5-(4-fluorophenyl)-1H,4H-thieno[2,3-d]pyrimidin-4-ylidene]methanamine (CAS 1030123-90-0)
- 1-{[2-(2H-1,3-Benzodioxol-5-yl)imidazo[1,2-a]pyridin-3-yl]methyl}piperidine-4-carboxylic acid (CAS 904814-29-5)
- 5-{[(2H-1,3-benzodioxol-5-yl)methyl]sulfamoyl}-2-ethoxybenzoic acid (CAS 866156-08-3)
- 1-{[2-(2H-1,3-Benzodioxol-5-yl)imidazo[1,2-a]pyrimidin-3-yl]methyl}piperidine-2-carboxylic acid (CAS 1029108-71-1)
- 1-{[2-(2H-1,3-Benzodioxol-5-yl)imidazo[1,2-a]pyrimidin-3-yl]methyl}piperidine-3-carboxylic acid (CAS 904816-50-8)
- 1-{[2-(2H-1,3-Benzodioxol-5-yl)imidazo[1,2-a]pyrimidin-3-yl]methyl}piperidine-4-carboxylic acid (CAS 912770-72-0)
- 3-(2H-1,3-Benzodioxol-5-yl)-3-(2,5-dimethyl-1H-pyrrol-1-yl)-N-(4-fluorophenyl)propanamide (CAS 866040-39-3)
- 1-[4-(2H-1,3-Benzodioxol-5-yloxy)but-2-yn-1-yl]-4-(4-methoxyphenyl)piperazine (CAS 866040-58-6)
Recommended Standards
- 1-(3,4-Dimethoxyphenyl)-4-(3-(m-tolyl)-1,2,4-oxadiazol-5-yl)pyrrolidin-2-one (CAS 941960-78-7)
- 1-(2-Fluorophenyl)-4-(4-(methylsulfonyl)-2-nitrophenyl)piperazine (CAS 852225-19-5)
- 11-(4-Hydroxy-3-nitrophenyl)-3,3-dimethyl-2,3,4,5,10,11-hexahydro-1H-dibenzo[b,e][1,4]diazepin-1-one (CAS 886650-42-6)
- 1-(2-Fluoro-4-nitrophenyl)-4-tosylpiperazine (CAS 385380-87-0)
- 4-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-2-methylbenzo[f][1,3,4]oxadiazepin-5(4H)-one (CAS 861210-70-0)
- 4-(1,1-Difluoroethyl)-1H-pyrazole (CAS 1785350-65-3)
- tert-Decanethiol (CAS 30174-58-4)
- N-Methyl-1-(5-methyl-2-thienyl)methanamine (CAS 82230-49-7)
- Crizotinib Impurity 73 (CAS CATO-C4X-102573)
- 5-Fluoro-2,4-dimethylpyridine (CAS 1806569-94-7)
- Doxorubicin Impurity 29 (CAS CATO-C4X-203329)
- 5-(n-Ethylsulfamoyl)-3-methylthiophene-2-carboxylic acid (CAS 1096321-53-7)
- Phytomenadione/Vitamin K1 Impurity 80 (CAS CATO-C4X-220780)
- D-Pro36-Tirzepatide (CAS CATO-CPTD788903)
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