2,2'-Methylenebis(4,4,5,5-tetramethyl-1,3,2-dioxaborolane) 78782-17-9 B4103 Bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)methane Bis[(pinacolato)boryl]methane CAS 78782-17-9

Purity 97%+In StockPharmaceutical Standards
CAS No.78782-17-9
Molecular FormulaC13H26B2O4
Molecular Weight267.97 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2,2'-Methylenebis(4,4,5,5-tetramethyl-1,3,2-dioxaborolane) 78782-17-9 B4103 Bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)methane Bis[(pinacolato)boryl]methane CAS 78782-17-9 chemical structure

Description

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

2,2'-Methylenebis(4,4,5,5-tetramethyl-1,3,2-dioxaborolane) 78782-17-9 B4103 Bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)methane Bis[(pinacolato)boryl]methane (CAS 78782-17-9) is a high-purity analytical reference standard with the molecular formula C13H26B2O4 and a molecular weight of 267.97 g/mol.

The molecular framework of 2,2'-Methylenebis(4,4,5,5-tetramethyl-1,3,2-dioxaborolane) 78782-17-9 B4103 Bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)methane Bis[(pinacolato)boryl]methane (C13H26B2O4) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

As a certified reference material (CRM), 2,2'-Methylenebis(4,4,5,5-tetramethyl-1,3,2-dioxaborolane) 78782-17-9 B4103 Bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)methane Bis[(pinacolato)boryl]methane meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC13H26B2O4
Molecular Weight267.97 g/mol
Purity97%+
StorageStore in a cool place (≤25°C), keep sealed and dry
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityHygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)1.0
CAS Registry Year (est.)1979

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