4-((4-(2-Chlorophenoxy)phenyl)amino)-4-oxobutanoic acid CAS 667446-82-4
| CAS No. | 667446-82-4 |
| Molecular Formula | C16H14ClNO4 |
| Molecular Weight | 319.74 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 4-((4-(2-Chlorophenoxy)phenyl)amino)-4-oxobutanoic acid is closely related to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
4-((4-(2-Chlorophenoxy)phenyl)amino)-4-oxobutanoic acid (CAS 667446-82-4), molecular formula C16H14ClNO4 and molecular weight 319.74 g/mol, is a CATO reference standard with documented purity and traceability.
4-((4-(2-Chlorophenoxy)phenyl)amino)-4-oxobutanoic acid (C16H14ClNO4) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 4-((4-(2-Chlorophenoxy)phenyl)amino)-4-oxobutanoic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H14ClNO4 |
| Molecular Weight | 319.74 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Chlorophenoxy Standards
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Recommended Standards
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- 55757-50-1 Iodo(2-~13~C)acetic acid DTXSID50745772 (CAS 55757-50-1)
- Semaglutide impurity 211 (CAS CATO-C4X-2226211)
- 6-Bromo-2-(tert-butoxy)-3-cyclopropoxypyridine (CAS 1243356-97-9)
- 2-((3-Chloropyrazin-2-yl)amino)-2-phenylethan-1-ol (CAS 1492628-35-9)
- 1-(3,5-Difluoro-4-propoxyphenyl)-2,2,2-trifluoroethan-1-one (CAS 1443332-21-5)
- 5,7-Difluoro-3-iodo-1-(phenylsulfonyl)-1H-indole (CAS 500139-01-5)
- (4-Nitrophenyl)(trimethylsilyl)methanone (CAS 75748-13-9)
- Neuropeptide Y (18-36) (CAS 114495-97-5)
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