2-Cyano-2-[(2Z)-pyrrolidin-2-ylidene]acetamide CAS 66751-23-3
| CAS No. | 66751-23-3 |
| Molecular Formula | C7H9N3O |
| Molecular Weight | 151.17 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2-Cyano-2-[(2Z)-pyrrolidin-2-ylidene]acetamide is closely related to an amide group, a hydroxyl group, an ether linkage, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
2-Cyano-2-[(2Z)-pyrrolidin-2-ylidene]acetamide (CAS 66751-23-3) is a high-purity analytical reference standard with the molecular formula C7H9N3O and a molecular weight of 151.17 g/mol.
The molecular framework of 2-Cyano-2-[(2Z)-pyrrolidin-2-ylidene]acetamide (C7H9N3O) is characterized by an amide group, a hydroxyl group, an ether linkage, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-Cyano-2-[(2Z)-pyrrolidin-2-ylidene]acetamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H9N3O |
| Molecular Weight | 151.17 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1976 |
| Nitrogen Atoms | 3 |
Related Cyano Standards
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Recommended Standards
- 2-Amino-N-methylpyridine-3-carboxamide (CAS 870997-87-8)
- 2-Ethyl-1H-pyrazolo[1,5-b][1,2,4]triazol-7-amine (CAS 227610-59-5)
- 2-amino-N-(pyridin-3-yl)acetamide (CAS 294888-93-0)
- 2-Methoxy-6,7-dihydro-5H-pyrrolo[3,4-d]pyrimidine (CAS 947305-13-7)
- Isomagnolol (CAS 87688-90-2)
- 2-Bromo-6-methyl-4-nitropyridine (CAS 97944-46-2)
- 2-Bromo-5-ethyl-1,3,4-thiadiazole (CAS 57709-49-6)
- 4-[(3-methyl-1,2,4-oxadiazol-5-yl)methyl]aniline hydrochloride (CAS 1461709-33-0)
- 3-(Chloromethyl)-5-(trifluoromethyl)-1,2,4-oxadiazole (CAS 890095-69-9)
- 2-Bromothiazolo[5,4-c]pyridin-4(5H)-one (CAS 1035219-80-7)
- 4-Picoline-N-oxide (CAS 1003-67-4)
- Pamatolol (CAS 59110-35-9)
- 3,4,5-Trihydroxybenzoicacid,magnesiumsalt dihydrate (CAS 1670250-44-8)
- Semaglutide impurity 24 (CAS CATO-C4X-222624)
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