3-(Chloromethyl)-5-(trifluoromethyl)-1,2,4-oxadiazole CAS 890095-69-9
| CAS No. | 890095-69-9 |
| Molecular Formula | C4H2ClF3N2O |
| Molecular Weight | 186.52 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures 3-(Chloromethyl)-5-(trifluoromethyl)-1,2,4-oxadiazole under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
3-(Chloromethyl)-5-(trifluoromethyl)-1,2,4-oxadiazole (CAS 890095-69-9) is a high-purity analytical reference standard with the molecular formula C4H2ClF3N2O and a molecular weight of 186.52 g/mol.
The molecular framework of 3-(Chloromethyl)-5-(trifluoromethyl)-1,2,4-oxadiazole (C4H2ClF3N2O) is characterized by an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C4H2ClF3N2O |
| Molecular Weight | 186.52 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloromethyl Standards
- 5-Chloromethyl-3-trifluoromethyl-[1,2,4]oxadiazole (CAS 100442-49-7)
- 5-(Chloromethyl)-2-hydroxybenzoic acid (CAS 10192-87-7)
- 2-(Chloromethyl)-4,6-dihydroxybenzaldehyde (CAS 378749-91-8)
- 2-(Chloromethyl)-2H-oxazolo[3,2-a]pyrimidin-7(3H)-one (CAS 131310-37-7)
- methyl 5-(chloromethyl)pyrazine-2-carboxylate (CAS 1824324-58-4)
- Methyl 4-(Chloromethyl)pyrimidine-2-carboxylate (CAS 1936261-46-9)
- Methyl 2-(chloromethyl)pyrimidine-5-carboxylate (CAS 944901-35-3)
- Methyl 6-(chloromethyl)pyrimidine-4-carboxylate (CAS 944902-43-6)
Recommended Standards
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- benzyl N-[(3S)-2-ethoxy-5-oxo-tetrahydrofuran-3-yl]carbamate (CAS 2820379-23-3)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com