Calcitriol Impurity 36 CAS 66774-84-3

Purity 97%+In StockPharmacopoeial Impurity Standards
CAS No.66774-84-3
Molecular FormulaC18H34O2
Molecular Weight282.46 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Calcitriol Impurity 36 CAS 66774-84-3 chemical structure

Description

As a process- or degradation-related impurity, Calcitriol Impurity 36 (CAS 66774-84-3, C18H34O2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.

Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, Calcitriol Impurity 36 is typically white to off-white crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 282.46 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC18H34O2
Molecular Weight282.46 g/mol
Purity97%+
StorageStore at room temperature
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityStable under recommended storage conditions
Degree of Unsaturation (DBE)2.0
CAS Registry Year (est.)1976

Related Calcitriol Standards

Recommended Standards

Why CATO?